Smoothing splines with varying smoothing parameter

Wang, X; Du, P; Shen, J

Some Advanced Model Selection Topics for Nonparametric/Semiparametric Models with High-Dimensional Data

Fang, Zaili (Virginia Tech, 2012-10-19)

Model and variable selection have attracted considerable attention in areas of application where datasets usually contain thousands of variables. Variable selection is a critical step to reduce the dimension of high ...

The Clarke Derivative and Set-Valued Mappings in the Numerical Optimization of Non-Smooth, Noisy Functions

Krahnke, Andreas (Virginia Tech, 2001-04-30)

In this work we present a new tool for the convergence analysis of numerical optimization methods. It is based on the concepts of the Clarke derivative and set-valued mappings. Our goal is to apply this tool to minimization ...

Dehydroepiandrosterone protects vascular endothelial cells against apoptosis through a G alpha(i) protein-dependent activation of phosphatidylinositol 3-kinase/Akt and regulation of antiapoptotic Bcl-2 expression

Liu, D. M.; Si, H. W.; Reynolds, K. A.; Zhen, W.; Jia, Z. Q.; Dillon, J. S. (Endocrine Society, 2007-07)

The adrenal steroid dehydroepiandrosterone (DHEA) may improve vascular function, but the mechanism is unclear. In the present study, we show that DHEA significantly increased cell viability, reduced caspase-3 activity, and ...