Show simple item record

dc.contributor.authorKaur, Gen_US
dc.contributor.authorPickrell, Gen_US
dc.contributor.authorKimsawatde, Gen_US
dc.contributor.authorHoma, Den_US
dc.contributor.authorAllbee, HAen_US
dc.contributor.authorSriranganathan, Nen_US
dc.date.accessioned2017-03-07T15:35:00Z
dc.date.available2017-03-07T15:35:00Z
dc.date.issued2014-03-18en_US
dc.identifier.citationKaur, G.; Pickrell, G.; Kimsawatde, G.; Homa, D.; Allbee, H. A.; Sriranganathan, N., "Synthesis, cytotoxicity, and hydroxyapatite formation in 27-Tris-SBF for sol-gel based CaO-P2O5-SiO2-B2O3-ZnO bioactive glasses," Scientific Reports 4:4392, (2014). DOI: 10.1038/srep04392.
dc.identifier.issn2045-2322en_US
dc.identifier.urihttp://hdl.handle.net/10919/75294
dc.description.abstractCaO-P2O5-SiO2-B2O3-ZnO bioactive glasses were prepared via an optimized sol-gel method. The current investigation was focused on producing novel zinc based calcium phosphoborosilicate glasses and to evaluate their mechanical, rheological, and biocompatible properties. The morphology and composition of these glasses were studied using X-ray diffraction (XRD) and scanning electron microscopy (SEM). The particle size, mechanical and flexural strength was also determined. Furthermore, the zeta potential of all the glasses were determined to estimate their flocculation tendency. The thermal analysis and weight loss measurements were carried out using differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) respectively. For assessing the in-vitro bioactive character of synthesized glasses, the ability for apatite formation on their surface upon their immersion in simulated body fluid (SBF) was checked using SEM and pH measurements. MTS assay cytotoxicity assay and live-dead cell viability test were conducted on J774A.1 cells murine macrophage cells for different glass concentrations.en_US
dc.format.extent? - ? (14) page(s)en_US
dc.format.mimetypeapplication/pdf
dc.languageEnglishen_US
dc.publisherNature Publishing Groupen_US
dc.relation.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000332937300001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=930d57c9ac61a043676db62af60056c1en_US
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0)*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/*
dc.subjectIN-VITRO BIOACTIVITYen_US
dc.subjectIONIC-STRENGTHen_US
dc.subjectZINCen_US
dc.subjectTEMPERATUREen_US
dc.subjectCERAMICSen_US
dc.subjectVIVOen_US
dc.subjectNANOPARTICLESen_US
dc.subjectBIOCERAMICSen_US
dc.subjectSCAFFOLDSen_US
dc.subjectKINETICSen_US
dc.titleSynthesis, cytotoxicity, and hydroxyapatite formation in 27-Tris-SBF for sol-gel based CaO-P2O5-SiO2-B2O3-ZnO bioactive glassesen_US
dc.typeArticle - Refereed
dc.description.versionPublished (Publication status)en_US
dc.title.serialScientific Reportsen_US
dc.identifier.doihttps://doi.org/10.1038/srep04392
dc.identifier.volume4en_US
dc.identifier.orcidPickrell, G [0000-0003-1782-9010]en_US
dc.type.dcmitypeText
pubs.organisational-group/Virginia Tech
pubs.organisational-group/Virginia Tech/All T&R Faculty
pubs.organisational-group/Virginia Tech/Engineering
pubs.organisational-group/Virginia Tech/Engineering/COE T&R Faculty
pubs.organisational-group/Virginia Tech/Engineering/Materials Science and Engineering
pubs.organisational-group/Virginia Tech/Veterinary Medicine
pubs.organisational-group/Virginia Tech/Veterinary Medicine/Biomedical Sciences and Pathobiology
pubs.organisational-group/Virginia Tech/Veterinary Medicine/CVM T&R Faculty


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0)
License: Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0)