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dc.contributor.authorZhu, Jie
dc.contributor.authorRodriguez-Corrales, José Á.
dc.contributor.authorPrussin, Reece
dc.contributor.authorZhao, Zongmin
dc.contributor.authorDominijanni, Anthony
dc.contributor.authorHopkins, Samantha L.
dc.contributor.authorWinkel, Brenda S.
dc.contributor.authorRobertson, John L.
dc.contributor.authorBrewer, Karen J.
dc.date.accessioned2017-05-01T06:42:16Z
dc.date.available2017-05-01T06:42:16Z
dc.date.issued2016-11-07
dc.identifierc6cc07978d.pdf
dc.identifierc6cc07978d1.pdf
dc.identifier.issn1359-7345
dc.identifier.urihttp://hdl.handle.net/10919/77547
dc.description.abstractThe mixed-metal supramolecular complex, [(Ph2phen)2Ru(dpp)PtCl2]2+, displays significant DNA modification, cell growth inhibition, and toxicity towards F98 malignant glioma cells following visible light irradiation. The design of this complex affords superior cellular uptake and antiproliferative activity compared to the classic chemotherapeutic agent, cisplatin.
dc.format.extent145-148
dc.format.mimetypeapplication/pdf
dc.language.isoen_US
dc.publisherRoyal Society of Chemistry
dc.relation.ispartofRoyal Society of Chemistry Gold Open Access - 2016
dc.rightsCC BY-NC 3.0
dc.rightsCreative Commons Attribution-NonCommercial 3.0 Unported
dc.rights.urihttps://creativecommons.org/licenses/by-nc/3.0/
dc.titleExploring the activity of a polyazine bridged Ru(ii)-Pt(ii) supramolecule in F98 rat malignant glioma cells
dc.typeArticle - Refereed
dc.rights.holderZhu, Jie
dc.rights.holderRodriguez-Corrales, José Á.
dc.rights.holderPrussin, Reece
dc.rights.holderZhao, Zongmin
dc.rights.holderDominijanni, Anthony
dc.rights.holderHopkins, Samantha L.
dc.rights.holderWinkel, Brenda S.
dc.rights.holderRobertson, John L.
dc.rights.holderBrewer, Karen J.
dc.contributor.departmentVirginia Tech. Department of Chemistry
dc.contributor.departmentVirginia Tech. School of Biomedical Engineering and Sciences
dc.contributor.departmentVirginia Tech. Department of Biological Systems Engineering
dc.contributor.departmentVirginia Tech. Department of Biological Sciences
dc.title.serialChemical Communications
dc.identifier.doihttps://doi.org/10.1039/c6cc07978d
dc.identifier.volume53
dc.identifier.issue1
dc.type.dcmitypeText
dc.type.dcmitypeDataset
dc.identifier.eissn1364-548X


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