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Minicell-based fungal RNAi delivery for sustainable crop protection
(2021-02)
Spray-induced gene silencing (SIGS) using topical dsRNA applications has risen as a promising, target-specific, and environmentally friendly disease management strategy against phytopathogenic fungi. However, dsRNA stability, ...
Touchscreens for Whom? Working Memory and Age Moderate the Impact of Contingency on Toddlers' Transfer From Video
(2021-02-24)
Toddlers exhibit poor transfer between video and real-world contexts. Contingently responsive video such as that found in touchscreen apps appears to assist transfer for some toddlers but not others. This study investigated ...
Evaluation of ebselen in resolving a methicillin-resistant Staphylococcus aureus infection of pressure ulcers in obese and diabetic mice
(2021-02-22)
Pressure ulcers (PUs) are a source of morbidity in individuals with restricted mobility including individuals that are obese or diabetic. Infection of PUs with pathogens, including methicillin-resistant Staphylococcus ...
Divergent age-dependent peripheral immune transcriptomic profile following traumatic brain injury
(Springer Nature, 2019-06-12)
The peripheral immune system is a major regulator of the pathophysiology associated with traumatic brain injury (TBI). While age-at-injury influences recovery from TBI, the differential effects on the peripheral immune ...
Age differences in functional network reconfiguration with working memory training
(2021-04-15)
Demanding cognitive functions like working memory (WM) depend on functional brain networks being able to communicate efficiently while also maintaining some degree of modularity. Evidence suggests that aging can disrupt ...
Positionality practices and dimensions of impact on equity research: A collaborative inquiry and call to the community
(2021-01)
Background Many engineering education researchers acknowledge that their positionality impacts their research. Practices for reporting positionality vary widely and rarely incorporate a nuanced discussion of the impact of ...
Residential Satisfaction of Rural Older Adults Aging in Place
(2021-02)
This study explored residential (housing and town) satisfaction of rural older adults aging in place, relating to demographic and housing characteristics. We conducted a structured, face-to-face survey with 149 rural older ...
Stabilization of a Broadly Neutralizing Anti-Chikungunya Virus Single Domain Antibody
(2021-01-28)
A single domain antibody (clone CC3) previously found to neutralize a vaccine strain of the chikungunya virus (PRNT50 = 2. 5 ng/mL) was found to be broadly neutralizing. Clone CC3 is not only able to neutralize a wild-type ...
Randomized Manipulation of Early Cognitive Experience Impacts Adult Brain Structure
(Massachusetts Institute of Technology, 2021)
Does early exposure to cognitive and linguistic stimulation impact brain structure? Or do genetic predispositions account for the co-occurrence of certain neuroanatomical phenotypes and a tendency to engage children in ...
DeepARG: a deep learning approach for predicting antibiotic resistance genes from metagenomic data
(2018-02-01)
Background
Growing concerns about increasing rates of antibiotic resistance call for expanded and comprehensive global monitoring. Advancing methods for monitoring of environmental media (e.g., wastewater, agricultural ...