Now showing items 1-20 of 840

    • 2019 SAIC National Security Education Program Colloquium 

      Unknown author (Virginia Tech. Hume Center., 2019-04-16)
      The annual National Security Education Program Colloquium is the highlight of our educational programs. It allows students from across the university to interact with leaders from the intelligence and national security ...
    • 7.0-T Magnetic Resonance Imaging Characterization of Acute Blood-Brain-Barrier Disruption Achieved with Intracranial Irreversible Electroporation 

      Garcia, Paulo A.; Rossmeisl, John H. Jr.; Robertson, John L.; Olson, JohnD.; Johnson, Annette J.; Ellis, Thomas L.; Davalos, Rafael V. (PLOS, 2012-11-30)
      The blood-brain-barrier (BBB) presents a significant obstacle to the delivery of systemically administered chemotherapeutics for the treatment of brain cancer. Irreversible electroporation (IRE) is an emerging technology ...
    • A Declarative Approach to Hardening Services Against QoS Vulnerabilities 

      Kwon, Young-Wo; Tilevich, Eli (IEEE, 2011)
      The Quality of Service (QoS) in a distributed service-oriented application can be negatively affected by a variety of factors. Network volatility, hostile exploits, poor service management, all can prevent a service-oriented ...
    • A developmental sex difference in hippocampal neurogenesis is mediated by endogenous Oestradiol 

      Bowers, J. Michael; Waddell, Jaylyn; McCarthy, Margaret M. (BMC, 2010)
      Background: Oestradiol is a steroid hormone that exerts extensive influence on brain development and is a powerful modulator of hippocampal structure and function. The hippocampus is a critical brain region regulating ...
    • A Framework for Occupancy Tracking in a Building via Structural Dynamics Sensing of Footstep Vibrations 

      Poston, Jeffrey D.; Buehrer, R. Michael; Tarazaga, Pablo A. (Frontiers, 2017-11-06)
      Counting the number of occupants in building areas over time—occupancy tracking— provides valuable information for responding to emergencies, optimizing thermal conditions or managing personnel. This capability is distinct ...
    • A human exposome framework for guiding risk management and holistic assessment of recycled water quality 

      Garner, Emily; Zhu, Ni; Strom, Laurel; Edwards, Marc A.; Pruden, Amy (Royal Society of Chemistry, 2016-04-12)
      Challenges associated with water scarcity and increasing water demand are leading many cities around the globe to consider water reuse as a step towards water sustainability. Recycled water may be used in a spectrum of ...
    • A Model for a Smallpox-Vaccination Policy 

      Bozzette, Samuel A.; Boer, Rob; Bhatnagar, Vibha; Brower, Jennifer L.; Keeler, Emmett B.; Morton, Sally C.; Stoto, Michael A. (NEJM Group, 2003-01-30)
      Background: The new reality of biologic terrorism and warfare has ignited a debate about whether to reintroduce smallpox vaccination. Methods: We developed scenarios of smallpox attacks and built a stochastic model of ...
    • A Modest Proposal for Open Market Risk Assessment to Solve the Cyber-Security Problem 

      O’Shea, Timothy J.; Mondl, Adam; Clancy, T. Charles (Virginia Tech, 2016-04-29)
      We introduce a model for a market based economic system of cyber-risk valuation to correct fundamental problems of incentives within the information technology and information processing industries. We assess the makeup ...
    • A Molecular Mechanism Regulating the Timing of Corticogeniculate Innervation 

      Brooks, Justin M.; Su, Jianmin; Levy, Carl; Wang, Jessica S.; Seabrook, Tania A.; Guido, William (Elsevier, 2013-11-14)
      Neural circuit formation demands precise timing of innervation by different classes of axons. However, the mechanisms underlying such activity remain largely unknown. In the dorsal lateral geniculate nucleus (dLGN), axons ...
    • A Multi-Tier Wireless Spectrum Sharing System Leveraging Secure Spectrum Auctions 

      Abdelhadi, Ahmed; Shajaiah, Haya; Clancy, Charles (IEEE, 2015-10-08)
      Secure spectrum auctions can revolutionize the spectrum utilization of cellular networks and satisfy the ever increasing demand for resources. In this paper, a multi-tier dynamic spectrum sharing system is studied for ...
    • A Simulation Optimization Approach to Epidemic Forecasting 

      Nsoesie, Elaine O.; Beckman, Richard J.; Shashaani, Sara; Nagaraj, Kalyani S.; Marathe, Madhav V. (PLOS, 2013-06-27)
      Reliable forecasts of influenza can aid in the control of both seasonal and pandemic outbreaks. We introduce a simulation optimization (SIMOP) approach for forecasting the influenza epidemic curve. This study represents ...
    • A systematic review of studies on forecasting the dynamics of influenza outbreaks 

      Nsoesie, Elaine O.; Brownstein, John S.; Ramakrishnan, Naren; Marathe, Madhav V. (Wiley, 2013-12-23)
      Forecasting the dynamics of influenza outbreaks could be useful for decision-making regarding the allocation of public health resources. Reliable forecasts could also aid in the selection and implementation of interventions ...
    • Aberrant Calcium Signaling in Astrocytes Inhibits Neuronal Excitability in a Human Down Syndrome Stem Cell Model 

      Mizuno, Grace O.; Wang, Yinxue; Shi, Guilai; Wang, Yizhi; Sun, Junqing; Papadopoulos, Stelios; Broussard, Gerard J.; Unger, Elizabeth K.; Deng, Wenbin; Weick, Jason; Bhattacharyya, Anita; Chen, Chao-Yin; Yu, Guoqiang; Looger, Loren L.; Tian, Lin (Elsevier, 2018-07-10)
      Down syndrome (DS) is a genetic disorder that causes cognitive impairment. The staggering effects associated with an extra copy of human chromosome 21 (HSA21) complicates mechanistic understanding of DS pathophysiology. ...
    • Active inference and agency: optimal control without cost functions 

      Friston, Karl; Samothrakis, Spyridon; Montague, P. Read (Springer, 2012-08-03)
      This paper describes a variational free-energy formulation of (partially observable) Markov decision problems in decision making under uncertainty. We show that optimal control can be cast as active inference. In active ...
    • Activity Dependent Protein Degradation Is Critical for the Formation and Stability of Fear Memory in the Amygdala 

      Jarome, Timothy J.; Werner, Craig T.; Kwapis, Janine L.; Helmstetter, Fred J. (PLOS, 2011-09)
      Protein degradation through the ubiquitin-proteasome system [UPS] plays a critical role in some forms of synaptic plasticity. However, its role in memory formation in the amygdala, a site critical for the formation of fear ...
    • Adaptive Brain and Behavior Across the Lifespan 

      Unknown author (Virginia Tech, 2016-05)
      Our aim is to understand adaptation and improve human lives in various contexts. Inequalities and environments in which people live affect their health and behavior — and their success of remaining healthy for a lifetime. ...
    • Adaptive Key Protection in Complex Cryptosystems with Attributes 

      Wang, Zilong; Yao, Danfeng (Daphne); Feng, Rongquan (Department of Computer Science, Virginia Polytechnic Institute & State University, 2012), TR-12-16
      In the attribute-based encryption (ABE) model, attributes (as opposed to identities) are used to encrypt messages, and all the receivers with qualifying attributes can decrypt the ciphertext. However, compromised attribute ...
    • Adoption of High-Performance Housing Technologies Among U.S. Homebuilding Firms, 2000 Through 2010 

      McCoy, Andrew P.; Koebel, C. Theodore; Sanderford, Andrew R.; Franck, Christopher T.; Keefe, Matthew J. (HUD, 2015)
      This article describes foundational processes of a larger project examining U.S. home builders’ choices to adopt innovative housing technologies that improve the environmental performance of new single-family homes. Home ...
    • Advancing the Global Land Grant Institution: Creating a Virtual Environment to Re-envision Extension and Advance GSS-related Research, Education, and Collaboration 

      Hall, Ralph P.; Polys, Nicholas F.; Sforza, Peter M.; Eubank, Stephen; Lewis, Bryan; Krometis, Leigh Anne Henry; Pollyea, Ryan; Schoenholtz, Stephen; Sridhar, Venkataramana; Crowder, Van; Lipsey, John; Christie, Maria Elisa; Glasson, George; Scherer, Hannah; Davis, Albert Jack; Dunay, Robert; King, Nathan T.; Muelenaer, Andre; Muelenaer, Penelope; Rist, Cassidy; Wenzel, Sophie (Virginia Tech, 2017-05-15)
      The vision for this project has emerged from several years of research, teaching, and service in Africa and holds the potential to internationalize education at Virginia Tech and in our partner institutions in Malawi. The ...
    • AERIS : Eco-Vehicle Speed Control at Signalized Intersections Using I2V Communication 

      Rakha, Hesham A.; Kamalanathsharma, Raj K.; Ahn, Kyoungho (United States. Joint Program Office for Intelligent Transportation Systems, 2012-06)
      This report concentrates on a velocity advisory tool, or decision support system, for vehicles approaching an intersection using communication capabilities between the infrastructure and vehicles. The system uses available ...