Now showing items 202-221 of 275

    • A Parametric Study Delineating Irreversible Electroporation from Thermal Damage Based on a Minimally Invasive Intracranial Procedure 

      Garcia, Paulo A.; Rossmeisl, John H.; Neal, Robert E., II; Ellis, Thomas L; Davalos, Rafael V. (2011-04-30)
      Background Irreversible electroporation (IRE) is a new minimally invasive technique to kill undesirable tissue in a non-thermal manner. In order to maximize the benefits from an IRE procedure, the pulse parameters and ...
    • Pathology of non-thermal irreversible electroporation (N-TIRE)-induced ablation of the canine brain 

      Rossmeisl, John H. Jr.; Garcia, Paulo A.; Roberston, John L.; Ellis, Thomas L.; Davalos, Rafael V. (KOREAN SOC VETERINARY SCIENCE, 2013-12-01)
      This study describes the neuropathologic features of normal canine brain ablated with non-thermal irreversible electroporation (N-TIRE). The parietal cerebral cortices of four dogs were treated with N-TIRE using a ...
    • Patient-derived glioblastoma stem cells respond differentially to targeted therapies 

      Kanabur, Pratik; Guo, Sujuan; Simonds, Gary S.; Kelly, Deborah F.; Gourdie, Robert G.; Verbridge, Scott; Sheng, Zhi (Impact Journals Llc, 2016-12-27)
      The dismal prognosis of glioblastoma is, at least in part, attributable to the difficulty in eradicating glioblastoma stem cells (GSCs). However, whether this difficulty is caused by the differential responses of GSCs to ...
    • Peak frequency in the theta and alpha bands correlates with human working memory capacity 

      Moran, Rosalyn; Campo, Pablo; Maestu, Fernando; Reilly, Richard B.; Dolan, Raymond J.; Strangle, Bryan A. (Frontiers, 2010-11-11)
      Theta oscillations in the local field potential of neural ensembles are considered key mediators of human working memory. Theoretical accounts arising from animal hippocampal recordings propose that the phase of theta ...
    • Peer Mediated Theatrical Engagement for Improving Reciprocal Social Interaction in Autism Spectrum Disorder 

      Corbett, Blythe A.; Qualls, Lydia R.; Valencia, Blythe; Fecteau, Stephanie; Swain, Deanna M. (Frontiers Media SA, 2014-10-10)
      The hallmark characteristic of autism spectrum disorder (ASD) is poor reciprocal social communication. Interventions designed to improve this core deficit are critically needed. Social skills interventions such as direct ...
    • Perceiving facial affective ambiguity: A behavioral and neural comparison of adolescents and adults. 

      Lee, Tae-Ho; Perino, Michael T.; McElwain, Nancy L.; Telzer, Eva H. (2019-01-10)
      The current study examined perceptual differences between adults and youth in perceiving ambiguous facial expressions. We estimated individuals' internal representation for facial expressions and compared it between age ...
    • Perineuronal nets decrease membrane capacitance of peritumoral fast spiking interneurons in a model of epilepsy 

      Tewari, Bhanu P.; Chaunsali, Lata; Campbell, Susan L.; Patel, Dipan C.; Goode, Adam E.; Sontheimer, Harald (Springer Nature, 2018-11-09)
      Brain tumor patients commonly present with epileptic seizures. We show that tumor-associated seizures are the consequence of impaired GABAergic inhibition due to an overall loss of peritumoral fast spiking interneurons ...
    • Phylogenetic Analysis of the SNORD116 Locus 

      Kocher, Matthew A.; Good, Deborah J. (MDPI, 2017-11-30)
      The SNORD116 small nucleolar RNA locus (SNORD116@) is contained within the long noncoding RNA host gene SNHG14 on human chromosome 15q11-q13. The SNORD116 locus is a cluster of 28 or more small ...
    • A Pilot Study of the Effects of Mindfulness-Based Cognitive Therapy on Positive Affect and Social Anxiety Symptoms 

      Strege, Marlene V.; Swain, Deanna; Bochicchio, Lauren; Valdespino, Andrew; Richey, John A. (Frontiers, 2018-06-01)
      Randomized controlled trials have demonstrated that mindfulness-based cognitive therapy (MBCT) is efficacious in reducing residual depressive symptoms and preventing future depressive episodes (Kuyken et al., 2016). One ...
    • Policy Adjustment in a Dynamic Economic Game 

      Li, Jian; McClure, Samuel M.; King-Casas, Brooks; Montague, P. Read (PLOS, 2006)
      Making sequential decisions to harvest rewards is a notoriously difficult problem. One difficulty is that the real world is not stationary and the reward expected from a contemplated action may depend in complex ways on ...
    • Policy Adjustment in a Dynamic Economic Game 

      Li, Jian; McClure, Samuel M.; King-Casas, Brooks; Montague, P. Read (PLOS, 2006-12)
      Making sequential decisions to harvest rewards is a notoriously difficult problem. One difficulty is that the real world is not stationary and the reward expected from a contemplated action may depend in complex ways on ...
    • Posttraumatic Stress Among Students After the Shootings at Virginia Tech 

      Hughes, Michael; Brymer, Melissa; Chiu, Wai Tat; Fairbank, John A.; Jones, Russell T.; Pynoos, Robert S.; Rothwell, Virginia; Steinberg, Alan M.; Kessler, Ronald C. (Psychological Trauma: Theory, Research, Practice, and Policy, 2011-07-18)
      On April 16, 2007, in the worst campus shooting incident in U.S. history, 49 students and faculty at Virginia Polytechnic Institute and State University (Virginia Tech) were shot, of whom 32 were killed. A cross-sectional ...
    • Pre-Synaptic Release Deficits in a DYT1 Dystonia Mouse Model 

      Yokoi, Fumiaki; Cheetham, Chad C.; Campbell, Susan L.; Sweatt, David J.; Li, Yuqing (PLOS, 2013-08)
      DYT1 early-onset generalized torsion dystonia (DYT1 dystonia) is an inherited movement disorder caused by mutations in one allele of DYT1 (TOR1A), coding for torsinA. The most common mutation is a trinucleotide deletion ...
    • Predictability Modulates Human Brain Response to Reward 

      Berns, Gregory S.; McClure, Samuel M.; Pagnoni, Guiseppe; Montague, P. Read (Society for Neuroscience, 2001-04-15)
      Certain classes of stimuli, such as food and drugs, are highly effective in activating reward regions. We show in humans that activity in these regions can be modulated by the predictability of the sequenced delivery of ...
    • Predicting Mild Traumatic Brain Injury with Injury Risk Functions 

      Young, Tyler (Brain Injuries and Biomechanics Symposium, 2013-09-19)
      To assess the safety of various products, equipment, and vehicles during traumatic events injury risk curves have been developed correlate measurable parameters with risk of injury. The first risk curves to predict head ...
    • Predicting the knowledge–recklessness distinction in the human brain 

      Vilares, Iris; Wesley, Michael J.; Ahn, Woo-Young; Hoffman, Morris; Jones, Owen D.; Morse, Stephen J.; Yaffe, Gideon; Lohrenz, Terry; Montague, P. Read; Bonnie, Richard J. (NAS, 2017-02-09)
      Criminal convictions require proof that a prohibited act was performed in a statutorily specified mental state. Different legal consequences, including greater punishments, are mandated for those who act in a state of ...
    • Predictive therapeutic planning for irreversible electroporation treatment of spontaneous malignant glioma 

      Garcia, Paulo A.; Kos, Bor; Rossmeisl, John H. Jr.; Pavliha, Denis; Miklavčič, Damijan; Davalos, Rafael V. (Wiley, 2017-07-25)
      Purpose: Irreversible electroporation (IRE) has been developed as a promising minimally invasive treatment to ablate spontaneous brain tumors with pulsed electric fields in canine patients. The purpose of the study is to ...
    • Predictors of Successful Weight Loss Maintenance: A Qualitative Comparative Analysis 

      Baugh, Mary E.; Savla, Jyoti Shital; Akers, Jeremy D.; Raynor, Hollie A.; Davy, Kevin P.; Davy, Brenda M. (Scientific Research, 2014-05)
      Individuals successful at weight loss maintenance (WTLM) utilize similar behaviors but in varying amounts and combinations. Research identifying characteristics which predict WTLM success could be used to develop effective ...
    • Primary Versus Secondary Diagnosis of Generalized Anxiety Disorder in Youth: Is the Distinction an Important One? 

      Ollendick, Thomas H.; Jarrett, Matthew A.; White, Bradley A.; White, Susan W.; Grills, Amie E. (Springer, 2016-08-01)
      Examine whether children with a primary diagnosis of generalized anxiety disorder (GAD) differ from children with a secondary diagnosis of GAD on clinician, parent, teacher, and youth-report measures. Based on consensus ...
    • Primed for Health: Future Thinking Priming Decreases Delay Discounting 

      Shevorykin, Mina; Pittman, Jami C.; Bickel, Warren K.; O'Connor, Richard J.; Malhotra, Ria; Prashad, Neelam; Sheffer, Christine E. (2019-07)
      Objective: Delay discounting, the propensity to devalue delayed rewards, has robust predictive validity for multiple health behaviors and is a new therapeutic target for health behavior change. Priming can influence behaviors ...