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    • Aberrant Calcium Signaling in Astrocytes Inhibits Neuronal Excitability in a Human Down Syndrome Stem Cell Model 

      Mizuno, Grace O.; Wang, Yinxue; Shi, Guilai; Wang, Yizhi; Sun, Junqing; Papadopoulos, Stelios; Broussard, Gerard J.; Unger, Elizabeth K.; Deng, Wenbin; Weick, Jason; Bhattacharyya, Anita; Chen, Chao-Yin; Yu, Guoqiang; Looger, Loren L.; Tian, Lin (Elsevier, 2018-07-10)
      Down syndrome (DS) is a genetic disorder that causes cognitive impairment. The staggering effects associated with an extra copy of human chromosome 21 (HSA21) complicates mechanistic understanding of DS pathophysiology. ...