Now showing items 1-4 of 4
Region- and Cell-Specific Expression of Transmembrane Collagens in Mouse Brain
Unconventional collagens are nonfribrillar proteins that not only contribute to the structure of extracellular matrices but exhibit unique bio-activities. Although roles for unconventional collagens have been well-established ...
LRRTM1 underlies synaptic convergence in visual thalamus
It has long been thought that the mammalian visual system is organized into parallel pathways, with incoming visual signals being parsed in the retina based on feature (e.g. color, contrast and motion) and then transmitted ...
Nuclei-specific differences in nerve terminal distribution, morphology, and development in mouse visual thalamus
Background: Mouse visual thalamus has emerged as a powerful model for understanding the mechanisms underlying neural circuit formation and function. Three distinct nuclei within mouse thalamus receive retinal input, the ...
Collagen-derived matricryptins promote inhibitory nerve terminal formation in the developing neocortex
(Rockefeller University Press, 2016-03-14)
Inhibitory synapses comprise only ∼20% of the total synapses in the mammalian brain but play essential roles in controlling neuronal activity. In fact, perturbing inhibitory synapses is associated with complex brain ...