Now showing items 31-40 of 96
New Agents for Targeting of IL-13RA2 Expressed in Primary Human and Canine Brain Tumors
Interleukin 13 receptor alpha 2 (IL-13RA2) is over-expressed in a vast majority of human patients with high-grade astrocytomas like glioblastoma. Spontaneous astrocytomas in dogs resemble human disease and have been proposed ...
Survival kinase genes present prognostic significance in glioblastoma
(Impact Journals Llc, 2016-04-12)
Associations between Parental Anxiety/Depression and Child Behavior Problems Related to Autism Spectrum Disorders: The Roles of Parenting Stress and Parenting Self-Efficacy
Parents of children with autism spectrum disorders (ASDs) have been shown to experience increases in stress, depression, and anxiety, which are also associated with child behavior problems related to ASDs. Literature-examining ...
Choosing Money over Drugs: The Neural Underpinnings of Difficult Choice in Chronic Cocaine Users
Addiction is considered a disorder that drives individuals to choose drugs at the expense of healthier alternatives. However, chronic cocaine users (CCUs)who meet addiction criteria retain the ability to choose money in ...
Diagnoses and characteristics of autism spectrum disorders in children with Prader-Willi syndrome
(Biomed Central Ltd, 2017-06-05)
Patient-derived glioblastoma stem cells respond differentially to targeted therapies
(Impact Journals Llc, 2016-12-27)
Contributions of VLDLR and LRP8 in the establishment of retinogeniculate projections
(BioMed Central, 2013-06-13)
Background: Retinal ganglion cells (RGCs), the output neurons of the retina, project to over 20 distinct brain nuclei, including the lateral geniculate nucleus (LGN), a thalamic region comprised of three functionally ...
Identification and Glycerol-Induced Correction of Misfolding Mutations in the X-Linked Mental Retardation Gene CASK
The overwhelming amount of available genomic sequence variation information demands a streamlined approach to examine known pathogenic mutations of any given protein. Here we seek to outline a strategy to easily classify ...
Whole Brain Radiation-Induced Impairments in Learning and Memory Are Time-Sensitive and Reversible by Systemic Hypoxia
Whole brain radiation therapy (WBRT) is commonly used for treatment of primary and metastatic brain tumors; however, cognitive impairment occurs in 40–50% of brain tumor survivors. The etiology of the cognitive impairment ...
High-frequency irreversible electroporation (H-FIRE) for non-thermal ablation without muscle contraction
Background Therapeutic irreversible electroporation (IRE) is an emerging technology for the non-thermal ablation of tumors. The technique involves delivering a series of unipolar electric pulses to permanently destabilize ...