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dc.contributor.authorLee, Tae-Ho
dc.contributor.authorTelzer, Eva H.
dc.date.accessioned2018-09-13T17:14:25Z
dc.date.available2018-09-13T17:14:25Z
dc.date.issued2016-06-17
dc.identifier.urihttp://hdl.handle.net/10919/85008
dc.description.abstractRecent developmental brain imaging studies have demonstrated that negatively coupled prefrontal-limbic circuitry implicates the maturation of brain development in adolescents. Using resting-state functional magnetic resonance imaging (rs-fMRI) and independent component analysis (ICA), the presentstudy examined functional network coupling between prefrontal and limbic systems and links toself-control and substance use onset in adolescents. Results suggest that negative network coupling(anti-correlated temporal dynamics) between the right fronto-parietal and limbic resting state net-works is associated with greater self-control and later substance use onset in adolescents. These findings increase our understanding of the developmental importance of prefrontal-limbic circuitry for adolescent substance use at the resting-state network level.
dc.description.sponsorshipNational Institute of Health
dc.description.sponsorshipNIH: R01DA039923
dc.format.extent8 pages
dc.format.mimetypeapplication/pdf
dc.language.isoen_US
dc.publisherElsevier
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAdolescence
dc.subjectRisk-taking behavior
dc.subjectResting-state fMRI
dc.subjectIndependent component analysis (ICA)
dc.subjectFronto-parietal network (FPN)
dc.subjectLimbic network
dc.subjectIntrinsic network connectivity
dc.titleNegative functional coupling between the right fronto-parietal and limbic resting state networks predicts increased self-control and later substance use onset in adolescence
dc.typeArticle - Refereed
dc.title.serialDevelopmental Cognitive Neuroscience
dc.identifier.doihttps://doi.org/10.1016/j.dcn.2016.06.002
dc.identifier.volume20
dc.type.dcmitypeText


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