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dc.contributor.authorWang, Geen_US
dc.contributor.authorZhang, Jieen_US
dc.contributor.authorGao, Haoen_US
dc.contributor.authorWeir, Victoren_US
dc.contributor.authorYu, Hengyongen_US
dc.contributor.authorCong, Wenxiangen_US
dc.contributor.authorXu, Xiaochenen_US
dc.contributor.authorShen, Haiouen_US
dc.contributor.authorBennett, Jamesen_US
dc.contributor.authorFurth, Marken_US
dc.contributor.authorWang, Yueen_US
dc.contributor.authorVannier, Michaelen_US
dc.date.accessioned2018-10-26T14:38:31Z
dc.date.available2018-10-26T14:38:31Z
dc.date.issued2012-06-29en_US
dc.identifier.othere39700en_US
dc.identifier.urihttp://hdl.handle.net/10919/85536
dc.description.abstractWe recently elevated interior tomography from its origin in computed tomography (CT) to a general tomographic principle, and proved its validity for other tomographic modalities including SPECT, MRI, and others. Here we propose “omni-tomography”, a novel concept for the grand fusion of multiple tomographic modalities for simultaneous data acquisition in a region of interest (ROI). Omni-tomography can be instrumental when physiological processes under investigation are multi-dimensional, multi-scale, multi-temporal and multi-parametric. Both preclinical and clinical studies now depend on in vivo tomography, often requiring separate evaluations by different imaging modalities. Over the past decade, two approaches have been used for multimodality fusion: Software based image registration and hybrid scanners such as PET-CT, PET-MRI, and SPECT-CT among others. While there are intrinsic limitations with both approaches, the main obstacle to the seamless fusion of multiple imaging modalities has been the bulkiness of each individual imager and the conflict of their physical (especially spatial) requirements. To address this challenge, omni-tomography is now unveiled as an emerging direction for biomedical imaging and systems biomedicine.en_US
dc.format.mimetypeapplication/pdfen_US
dc.language.isoen_USen_US
dc.publisherPLOSen_US
dc.rightsCreative Commons Attribution 4.0 Internationalen_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.titleTowards Omni-Tomography-Grand Fusion of Multiple Modalities for Simultaneous Interior Tomographyen_US
dc.typeArticle - Refereeden_US
dc.description.versionPeer Revieweden_US
dc.title.serialPLOS ONEen_US
dc.identifier.doihttps://doi.org/10.1371/journal.pone.0039700en_US
dc.identifier.volume7en_US
dc.identifier.issue6en_US
dc.type.dcmitypeTexten_US
dc.identifier.pmid22768108en_US
dc.identifier.eissn1932-6203en_US


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Creative Commons Attribution 4.0 International
License: Creative Commons Attribution 4.0 International