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dc.contributor.authorWattam, Alice R.
dc.contributor.authorAbraham, David
dc.contributor.authorDalay, Oral
dc.contributor.authorDisz, Terry L.
dc.contributor.authorDriscoll, Timothy
dc.contributor.authorGabbard, Joseph L.
dc.contributor.authorGillespie, Joseph J.
dc.contributor.authorGough, Roger
dc.contributor.authorHix, Deborah
dc.contributor.authorKenyon, Ronald
dc.contributor.authorMachi, Dustin
dc.contributor.authorMao, Chunhong
dc.contributor.authorNordberg, Eric K.
dc.contributor.authorOlson, Robert
dc.contributor.authorOverbeek, Ross
dc.contributor.authorPusch, Gordon D.
dc.contributor.authorShukla, Maulik
dc.contributor.authorSchulman, Julie
dc.contributor.authorStevens, Rick L.
dc.contributor.authorSullivan, Daniel E.
dc.contributor.authorVonstein, Veronika
dc.contributor.authorWarren, Andrew
dc.contributor.authorWill, Rebecca
dc.contributor.authorWilson, Meredith J. C.
dc.contributor.authorYoo, Hyun Seung
dc.contributor.authorZhang, Chengdong
dc.contributor.authorZhang, Yan
dc.contributor.authorSobral, Bruno W.
dc.date.accessioned2019-04-12T14:55:19Z
dc.date.available2019-04-12T14:55:19Z
dc.date.issued2014-01
dc.identifier.issn0305-1048
dc.identifier.urihttp://hdl.handle.net/10919/88954
dc.description.abstractThe Pathosystems Resource Integration Center (PATRIC) is the all-bacterial Bioinformatics Resource Center (BRC) (http://www.patricbrc.org). A joint effort by two of the original National Institute of Allergy and Infectious Diseases-funded BRCs, PATRIC provides researchers with an online resource that stores and integrates a variety of data types [e. g. genomics, transcriptomics, protein-protein interactions (PPIs), three-dimensional protein structures and sequence typing data] and associated metadata. Datatypes are summarized for individual genomes and across taxonomic levels. All genomes in PATRIC, currently more than 10 000, are consistently annotated using RAST, the Rapid Annotations using Subsystems Technology. Summaries of different data types are also provided for individual genes, where comparisons of different annotations are available, and also include available transcriptomic data. PATRIC provides a variety of ways for researchers to find data of interest and a private workspace where they can store both genomic and gene associations, and their own private data. Both private and public data can be analyzed together using a suite of tools to perform comparative genomic or transcriptomic analysis. PATRIC also includes integrated information related to disease and PPIs. All the data and integrated analysis and visualization tools are freely available. This manuscript describes updates to the PATRIC since its initial report in the 2007 NAR Database Issue.en_US
dc.description.sponsorshipNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Service [HHSN272200900040C]
dc.format.mimetypeapplication/pdf
dc.language.isoen_US
dc.rightsCreative Commons Attribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectmolecular interaction database
dc.subjectantibiotic-resistance genes
dc.subjectinfectious-diseases
dc.subjectstructural genomics
dc.subjectpathogen database
dc.subjectvirulence factors
dc.subjectdata sets
dc.subjectupdate
dc.subjectintegration
dc.subjecttools
dc.titlePATRIC, the bacterial bioinformatics database and analysis resourceen_US
dc.typeArticle - Refereed
dc.description.notesFunding for open access charge: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Service [Contract No. HHSN272200900040C].
dc.title.serialNucleic Acids Research
dc.identifier.doihttps://doi.org/10.1093/nar/gkt1099
dc.identifier.volume42
dc.identifier.issueD1
dc.type.dcmitypeText
dc.identifier.pmid24225323
dc.identifier.eissn1362-4962


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Creative Commons Attribution 4.0 International
License: Creative Commons Attribution 4.0 International