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dc.contributor.authorDriscoll, Tim
dc.contributor.authorDyer, Matthew D.
dc.contributor.authorMurali, T. M.
dc.contributor.authorSobral, Bruno W.
dc.date.accessioned2019-04-18T14:46:57Z
dc.date.available2019-04-18T14:46:57Z
dc.date.issued2009-01
dc.identifier.issn0305-1048
dc.identifier.urihttp://hdl.handle.net/10919/89032
dc.description.abstractProtein-protein interactions (PPIs) play a vital role in initiating infection in a number of pathogens. Identifying which interactions allow a pathogen to infect its host can help us to understand methods of pathogenesis and provide potential targets for therapeutics. Public resources for studying host pathogen systems, in particular PPIs, are scarce. To facilitate the study of host-pathogen PPIs, we have collected and integrated host-pathogen PPI (HP-PPI) data from a number of public resources to create the Pathogen Interaction Gateway (PIG). PIG provides a text based search and a BLAST interface for searching the HP-PPI data. Each entry in PIG includes information such as the functional annotations and the domains present in the interacting proteins. PIG provides links to external databases to allow for easy navigation among the various websites. Additionally, PIG includes a tool for visualizing a single HP-PPI network or two HP-PPI networks. PIG can be accessed at http://pig.vbi.vt.edu.en_US
dc.description.sponsorshipNational Institute of Allergy and Infectious Diseases [HHSN26620040035C]; NIH
dc.format.mimetypeapplication/pdf
dc.language.isoen_US
dc.rightsCreative Commons Attribution-NonCommercial 2.0
dc.rights.urihttps://creativecommons.org/licenses/by-nc/2.0/
dc.subjectmolecular interaction database
dc.subjectprotein
dc.subjectresource
dc.subjectupdate
dc.titlePIG-the pathogen interaction gatewayen_US
dc.typeArticle - Refereed
dc.description.notesNational Institute of Allergy and Infectious Diseases grant HHSN26620040035C. Funding for open access charge: NIH grant.
dc.title.serialNucleic Acids Research
dc.identifier.doihttps://doi.org/10.1093/nar/gkn799
dc.identifier.volume37
dc.type.dcmitypeText
dc.identifier.pmid18984614
dc.identifier.eissn1362-4962


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