Public college and university leaders will enter a state policy landscape in 2018 marked by more political uncertainty than any time in recent memory. The immediate driver of state-level uncertainty is the overhaul of the federal tax code signed by President Donald Trump in late 2017. This report provides a review of higher education policy issues that legislators and governors are mostly likely to discuss. This 11th annual assessment of state higher education policy issues includes a mix of new issues—such as federal policy changes—and longstanding policy debates, such as budgets, guns on campus, performance funding and immigration. Newspaper articles, economic forecasts, gubernatorial addresses, and the 2017 state legislative sessions informed this analysis.