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    • Method for the conversion of cephalomannine to taxol and for the preparation of n-acyl analogs of taxol 

      Chemistry; Center for Drug Discovery; Virginia Polytechnic Institute and State University; Kingston, David G.; Molinero, Anthony A.; Gunatilaka, A. Leslie (United States Patent and Trademark Office, 1995-11-28)
      The natural product cephalomannine can be converted to the important anticancer natural product taxol by a simple process involving the steps of dihydroxylation to give cephalomannine-diols, diol cleavage, benzoylation at ...