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dc.contributor.authorFusco da Costa, Ana Robertaen
dc.contributor.authorFalkinham, Joseph O. IIIen
dc.contributor.authorLopes, Maria L.en
dc.contributor.authorBarretto, Adriana R.en
dc.contributor.authorFelicio, Joao Soaresen
dc.contributor.authorMessias Sales, Lucia H.en
dc.contributor.authorda Costa Bahia, Jeann R.en
dc.contributor.authorConceicao, Emilyn C.en
dc.contributor.authorBatista Lima, Karla V.en
dc.date.accessioned2019-08-12T17:01:44Zen
dc.date.available2019-08-12T17:01:44Zen
dc.date.issued2013-07en
dc.identifier.issn1935-2735en
dc.identifier.othere2340en
dc.identifier.urihttp://hdl.handle.net/10919/93030en
dc.description.abstractThe majority of investigations of the epidemiology of nontuberculous mycobacteria (NTM) have focused on highly developed nations with a low prevalence of tuberculosis. In contrast, the Para state of north Brazil represents an area of high tuberculosis prevalence and increasing NTM incidence. Toward the goal of understanding the dynamics of infection by all Mycobacterium species, we report patient characteristics and the identification of NTM strains isolated from sputum samples from patients that were residents of Para, a state in the Amazon region, Northern of Brazil, over the period January 2010 through December 2011 (2 years). The 29 NTM patients comprised 13.5% of positive mycobacterial cultures over the 2-year period. A major risk factor for NTM pulmonary disease was previous tuberculosis (76%). Further, the average age of NTM patients (52 years) was significantly higher than that of tuberculosis patients (39 years) and more were female (72.4% vs. 37.4%). Unlike other Brazilian states, NTM pulmonary patients in Para were infected with a different spectrum of mycobacteria; primarily the rapidly growing Mycobacterium massiliense and Mycobacterium simiae complex.en
dc.description.sponsorshipCoordenacao de Aperfeicoamento de Pessoal de Nivel Superior; Conselho Nacional de Desenvolvimento Cientifico e Tecnologico; Evandro Chagas Institute, Ananindeua, Para, Brazilen
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherPLOSen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectthin-section cten
dc.subjectavium complexen
dc.subjectlung-diseaseen
dc.subjectunited-statesen
dc.subjectepidemiologyen
dc.subjectintracellulareen
dc.subjectfeaturesen
dc.subjectprevalenceen
dc.subjectspectrumen
dc.subjectchimeraen
dc.titleOccurrence of Nontuberculous Mycobacterial Pulmonary Infection in an Endemic Area of Tuberculosisen
dc.typeArticle - Refereeden
dc.contributor.departmentBiological Sciencesen
dc.description.notesThis work was supported by the Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior, the Conselho Nacional de Desenvolvimento Cientifico e Tecnologico and the Evandro Chagas Institute, Ananindeua, Para, Brazil. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.en
dc.title.serialPLOS Neglected Tropical Diseasesen
dc.identifier.doihttps://doi.org/10.1371/journal.pntd.0002340en
dc.identifier.volume7en
dc.identifier.issue7en
dc.type.dcmitypeTexten
dc.type.dcmitypeStillImageen
dc.identifier.pmid23875055en


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Creative Commons Attribution 4.0 International
License: Creative Commons Attribution 4.0 International