Show simple item record

dc.contributor.authorMartin, Rebekah L.en
dc.contributor.authorStrom, Owen R.en
dc.contributor.authorPruden, Amyen
dc.contributor.authorEdwards, Marc A.en
dc.date.accessioned2020-09-08T13:25:52Zen
dc.date.available2020-09-08T13:25:52Zen
dc.date.issued2020-09-04en
dc.identifier.citationMartin, R.L.; Strom, O.R.; Pruden, A.; Edwards, M.A. Interactive Effects of Copper Pipe, Stagnation, Corrosion Control, and Disinfectant Residual Influenced Reduction of Legionella pneumophila during Simulations of the Flint Water Crisis. Pathogens 2020, 9, 730.en
dc.identifier.urihttp://hdl.handle.net/10919/99926en
dc.description.abstractFlint, MI experienced two outbreaks of Legionnaires’ Disease (LD) during the summers of 2014 and 2015, coinciding with use of Flint River as a drinking water source without corrosion control. Using simulated distribution systems (SDSs) followed by stagnant simulated premise (i.e., building) plumbing reactors (SPPRs) containing cross-linked polyethylene (PEX) or copper pipe, we reproduced trends in water chemistry and Legionella proliferation observed in the field when Flint River versus Detroit water were used before, during, and after the outbreak. Specifically, due to high chlorine demand in the SDSs, SPPRs with treated Flint River water were chlorine deficient and had elevated L. pneumophila numbers in the PEX condition. SPPRs with Detroit water, which had lower chlorine demand and higher residual chlorine, lost all culturable L. pneumophila within two months. L. pneumophila also diminished more rapidly with time in Flint River SPPRs with copper pipe, presumably due to the bacteriostatic properties of elevated copper concentrations caused by lack of corrosion control and stagnation. This study confirms hypothesized mechanisms by which the switch in water chemistry, pipe materials, and different flow patterns in Flint premise plumbing may have contributed to observed LD outbreak patterns.en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherMDPIen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectflinten
dc.subjectLegionella pneumophilaen
dc.subjectcopperen
dc.subjectPEXen
dc.subjectironen
dc.subjectchlorineen
dc.subjectpremise plumbingen
dc.titleInteractive Effects of Copper Pipe, Stagnation, Corrosion Control, and Disinfectant Residual Influenced Reduction of Legionella pneumophila during Simulations of the Flint Water Crisisen
dc.typeArticle - Refereeden
dc.date.updated2020-09-07T22:00:25Zen
dc.description.versionPublished versionen
dc.contributor.departmentCivil and Environmental Engineeringen
dc.title.serialPathogensen
dc.identifier.doihttps://doi.org/10.3390/pathogens9090730en
dc.type.dcmitypeTexten
dc.type.dcmitypeStillImageen


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

Creative Commons Attribution 4.0 International
License: Creative Commons Attribution 4.0 International