Epstein, Leonard H.Jimenez-Knight, TatianaHonan, Anna M.Paluch, Rocco A.Bickel, Warren K.2022-09-272022-09-272022-01-011177-889X342118 (PII)http://hdl.handle.net/10919/112010Purpose: Medication nonadherence is prevalent in diabetic populations, with “forgetting” a commonly cited reason. This issue of forgetfulness is due, in part, to a failure of prospective memory (PM). Episodic future thinking (EFT) has been shown to improve PM but has not been used to improve medication adherence. Patients and Methods: The current study used a multiple baseline design (N = 4) to test the effects of EFT on medication non-adherence for four patients with a diagnosis of type 2 diabetes or prediabetes, with comorbid high blood pressure or high cholesterol. Medication adherence was objectively measured over 15 weeks using medication event monitoring systems. Results: Results of visual analysis showed medication adherence was reliably improved, confirmed by mixed model analysis of variance (p < 0.001), with significant differences from baseline to treatment (Tau <0.05) for 3 of 4 participants. Improvements in two measures of PM (effect size (ES) = 0.73, 0.80) and delay discounting (ES = 1.20) were observed. Conclusion: This study provides a feasible way to improve medication adherence in patients with prediabetes or type 2 diabetes.Pages 95-10410 page(s)application/pdfenCreative Commons Attribution-NonCommercial 4.0 Internationalepisodic future thinkingprediabetesprospective memorymedicationadherencePROSPECTIVE MEMORY PERFORMANCEINDIVIDUAL TIME-PREFERENCESBLOCK-TAPPING TASKVIRTUAL WEEKOLDERHEALTHADULTSASSOCIATIONIMPULSIVITYMECHANISMSmedication adherenceClinical ResearchBehavioral and Social ScienceDiabetesMetabolic and endocrineArticle - Refereed2022-09-26https://doi.org/10.2147/PPA.S34211816Bickel, Warren [0000-0002-1048-7372]350466451177-889X