Pitzer, Kevin K.2014-03-142014-03-141995etd-06062008-155317http://hdl.handle.net/10919/38104A versatile method for the preparation of 2-amino-2-deoxy-, 3-amino-3-deoxy-, 4- amino-4-deoxy-, and 5-amino-5-deoxy-sugars from noncarbohydrate precursors, halobenzenes 1 (Figure 1), has been developed. See: Figure 1: Aminosugar Targets from Halobenzenes This methodology has also been applied to achieve the synthesis of protected D-mannose- 2,3,4,5,6-d₅ 191, and derivatives thereof, from the metabolite d₅- bromocyclohexadiene-cis-diol 189 obtained from the microbial oxidation of d₅- bromobenzene 2 (Figure 2). See: Figure 2: Perdeuterated Sugar Synthesisx, 186 leavesBTDapplication/pdfenIn CopyrightLD5655.V856 1995.P589Dissertationhttp://scholar.lib.vt.edu/theses/available/etd-06062008-155317/