Cohen, AlasdairRasheduzzaman, MdDarling, AmandaKrometis, Leigh-Anne H.Edwards, Marc A.Brown, TeresaAhmed, TahminaWettstone, ErinPholwat, SupornTaniuchi, MamiRogawski McQuade, Elizabeth T.2022-07-262022-07-262022-07-15Cohen, A.; Rasheduzzaman, M.; Darling, A.; Krometis, L.-A.; Edwards, M.; Brown, T.; Ahmed, T.; Wettstone, E.; Pholwat, S.; Taniuchi, M.; Rogawski McQuade, E.T. Bottled and Well Water Quality in a Small Central Appalachian Community: Household-Level Analysis of Enteric Pathogens, Inorganic Chemicals, and Health Outcomes in Rural Southwest Virginia. Int. J. Environ. Res. Public Health 2022, 19, 8610.http://hdl.handle.net/10919/111364Consumption of unsafe drinking water is associated with a substantial burden of disease globally. In the US, ~1.8 million people in rural areas lack reliable access to safe drinking water. Our objective was to characterize and assess household-level water sources, water quality, and associated health outcomes in Central Appalachia. We collected survey data and water samples (tap, source, and bottled water) from consenting households in a small rural community without utility-supplied water in southwest Virginia. Water samples were analyzed for physicochemical parameters, total coliforms, <i>E. coli</i>, nitrate, sulfate, metals (e.g., arsenic, cadmium, lead), and 30+ enteric pathogens. Among the 69% (<i>n</i> = 9) of households that participated, all had piped well water, though 67% (<i>n</i> = 6) used bottled water as their primary drinking water source. Total coliforms were detected in water samples from 44.4% (<i>n</i> = 4) of homes, <i>E. coli</i> in one home, and enteric pathogens (<i>Aeromonas</i>, <i>Campylobacter</i>, <i>Enterobacter</i>) in 33% (<i>n</i> = 3) of homes. Tap water samples from 11% (<i>n</i> = 1) of homes exceeded the EPA MCL for nitrate, and 33% (<i>n</i> = 3) exceeded the EPA SMCL for iron. Among the 19 individuals residing in study households, reported diarrhea was 25% more likely in homes with measured <i>E. coli</i> and/or specific pathogens (risk ratio = 1.25, cluster-robust standard error = 1.64, <i>p</i> = 0.865). Although our sample size was small, our findings suggest that a considerable number of lower-income residents without utility-supplied water in rural areas of southwest Virginia may be exposed to microbiological and/or chemical contaminants in their water, and many, if not most, rely on bottled water as their primary source of drinking water.application/pdfenCreative Commons Attribution 4.0 Internationaldrinking waterenvironmental healthenteric pathogensmetalswell waterbottled waterrural healthVirginiaAppalachiaArticle - Refereed2022-07-25https://doi.org/10.3390/ijerph19148610