New artificial fluoro-cofactor of hydride transfer with novel fluorescence assay for redox biocatalysis

Zhang, LeiYuan, JunXu, Y.Zhang, Y. H. PercivalQian, Xuhong2016-12-222016-12-222016-01-011359-7345http://hdl.handle.net/10919/73802A new artificial fluoro-cofactor was developed for the replacement of natural cofactors NAD(P), exhibiting a high hydride transfer ability. More importantly, we established a new and fast screening method for the evaluation of the properties of artificial cofactors based on the fluorescence assay and visible color change.6471 - 6474 (4) page(s)application/pdfenIn CopyrightChemistry, MultidisciplinaryChemistryBIOMIMETIC ASYMMETRIC HYDROGENATION1,4-NADH DERIVATIVESBIOORGANOMETALLIC CHEMISTRYREGIOSELECTIVE REDUCTIONMEDICINAL CHEMISTRYMECHANISTIC ASPECTSNAD(P)H OXIDASENAD(+) MODELSREGENERATIONNICOTINAMIDENew artificial fluoro-cofactor of hydride transfer with novel fluorescence assay for redox biocatalysisArticle - RefereedChemical Communicationshttps://doi.org/10.1039/c6cc02002j5238