Mir, Adil ShamimNguyen, Vu Q.Soliman, YoussefSorrentino, Dario2021-06-242021-06-242021-06-23Mir, A.; Nguyen, V.Q.; Soliman, Y.; Sorrentino, D. Wireless Capsule Endoscopy for Diagnosis and Management of Post-Operative Recurrence of Crohn’s Disease. Life 2021, 11, 602.http://hdl.handle.net/10919/103994Despite aggressive medical therapy, many patients with Crohn’s disease require surgical intervention over time. After surgical resection, disease recurrence is common. Ileo-colonoscopy and the Rutgeerts score are commonly used for diagnosis and monitoring of post-operative endoscopic recurrence. The latter is the precursor of clinical recurrence and therefore it impacts prognosis and patient management. However, due to the limited length of bowel assessed by ileo-colonoscopy, this procedure can miss out-of-reach, more proximal lesions in the small bowel. This limitation introduces an important uncertainty when evaluating post-operative relapse by ileo-colonoscopy. In addition, the Rutgeerts score ‘per se’ bears a number of ambiguities. Here we will discuss the pros and cons of ileo-colonoscopy and other imaging studies including wireless capsule endoscopy to diagnose and manage post-operative recurrence of Crohn’s disease. A number of studies provide evidence that wireless capsule endoscopy is a potentially more accurate as well as less invasive and less costly alternative to conventional techniques including ileo-colonoscopy.application/pdfenCreative Commons Attribution 4.0 InternationalCrohn’s diseasecapsule endoscopyileo-colonoscopypost-operative Crohn’s diseaseArticle - Refereed2021-06-24https://doi.org/10.3390/life11070602