Bi, Feng Jr.2014-03-142014-03-141998-08-04etd-71498-12035http://hdl.handle.net/10919/36903This thesis describes the synthesis of the C1'-C10' portion 72 of the pamamycin-621A using a cuprate conjugate addition to join enone fragment 52 and organostannane fragment 64a. Fragments 52 and 64a were both synthesized from (S)-methylketene dimer 51.In CopyrightPamamycinLower PortionSynthesisKeteneThesishttp://scholar.lib.vt.edu/theses/available/etd-71498-12035/