Chan, Ryan2018-06-042018-06-042018-05-03http://hdl.handle.net/10919/83448With the continued evolution of MEMS-based gas chromatography, the drive to develop new standalone systems with lower power consumptions and higher portability has increased. However, with improvements come tradeoffs, and trying to reduce the pressure drop requirements of previously reported semi-packed columns causes a significant sacrifice in separation efficiency. This thesis covers the techniques for evaluating the separation column in a gas chromatography system as well as the important parameters that have the most effect on a column’s efficiency. Ionic liquids are introduced as a stable and versatile stationary phase for micro separation columns. It then describes a MEMS-based separation column design utilizing density modulation of embedded micro-pillars which attempts to optimize the balance between separation efficiency and pressure drop.ETDen-USCreative Commons Attribution-NonCommercial-NoDerivs 3.0 United StatesMEMSgas chromatographyseparation columndensity modulatedmicro pillarsThesis