Huang, Li JunLaw, Jeffrey N.Murali, T. M.2020-11-032020-11-032018-06-12Huang LJ, Law JN and Murali TM. Automating the PathLinker app for Cytoscape [version 1; peer review: 2 approved] F1000Research 2018, 7:727 https://doi.org/10.12688/f1000research.14616.1http://hdl.handle.net/10919/100777PathLinker is a graph-theoretic algorithm originally developed to reconstruct the interactions in a signaling pathway of interest. It efficiently computes multiple short paths within a background protein interaction network from the receptors to transcription factors (TFs) in a pathway. Since December 2015, PathLinker has been available as an app for Cytoscape. This paper describes how we automated the app to use the CyRest infrastructure and how users can incorporate PathLinker into their software pipelines.9 pagesapplication/pdfenCreative Commons Attribution 4.0 InternationalNetwork BiologyShortest PathsPathway ReconstructionCyREST APIArticle - Refereedhttps://doi.org/10.12688/f1000research.14616.17727