Davis, James J.Wattam, Alice R.Aziz, Ramy K.Brettin, ThomasButler, RalphButler, Rory M.Chlenski, PhilippeConrad, NealDickerman, Allan W.Dietrich, Emily M.Gabbard, Joseph L.Gerdes, SvetlanaGuard, AndrewKenyon, Ronald W.Machi, DustinMao, ChunhongMurphy-Olson, Daniel E.Nguyen, MarcusNordberg, Eric K.Olsen, Gary J.Olson, Robert D.Overbeek, Jamie C.Overbeek, RossParrello, BrucePusch, Gordon D.Shukla, MaulikThomas, ChrisVanOeffelen, MargoVonstein, VeronikaWarren, Andrew S.Xia, FangfangXie, DawenYoo, HyunseungStevens, Rick L.2020-05-272020-05-272020-01-080305-1048http://hdl.handle.net/10919/98561The PathoSystems Resource Integration Center (PATRIC) is the bacterial Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious Diseases (https://www.patricbrc.org). PATRIC supports bioinformatic analyses of all bacteria with a special emphasis on pathogens, offering a rich comparative analysis environment that provides users with access to over 250 000 uniformly annotated and publicly available genomes with curated metadata. PATRIC offers web-based visualization and comparative analysis tools, a private workspace in which users can analyze their own data in the context of the public collections, services that streamline complex bioinformatic workflows and command-line tools for bulk data analysis. Over the past several years, as genomic and other omics-related experiments have become more cost-effective and widespread, we have observed considerable growth in the usage of and demand for easy-to-use, publicly available bioinformatic tools and services. Here we report the recent updates to the PATRIC resource, including new web-based comparative analysis tools, eight new services and the release of a command-line interface to access, query and analyze data.application/pdfenCreative Commons CC0 1.0 Universal Public Domain DedicationArticle - Refereedhttps://doi.org/10.1093/nar/gkz94348D1316675201362-4962