ChemistryCenter for Drug DiscoveryZhang, WenyuBryson, David I.Crumpton, Jason B.Wynn, Jessica E.Santos, Webster L.2015-04-202015-04-202013-02-07Zhang, W., Bryson, D. I., Crumpton, J. B., Wynn, J., & Santos, W. L. (2013). Branched peptideboronic acids (BPBAs): a novel mode of binding towards RNA. Chemical Communications, 49(24), 2436-2438. doi: 10.1039/C3CC00243H1359-7345http://hdl.handle.net/10919/51702We report branched peptideboronic acids (BPBAs) that bind to RRE IIB from an on-bead high-throughput screening of a 3.3.4-library (46 656 compounds). We demonstrate that boronic acids are tunable moieties that afford a novel binding mode towards RNA.application/pdfen-USCreative Commons Attribution-NonCommercial 3.0 UnportedHIVAIDSRNABoronic acid moietiesBranched peptide boronic acids (BPBAs)Article - Refereedhttp://pubs.rsc.org/en/content/articlelanding/2013/cc/c3cc00243hhttps://doi.org/10.1039/C3CC00243H