Lester, Randall Vaughn2017-03-102017-03-101973http://hdl.handle.net/10919/76383This study presented the development and in vitro analysis of the Arp Hembrane Type Blood Oxygenator and a ventricle type blood pump. The system is designed for newborns suffering from Respiratory Distress Syndrome (R.D.S.), especially the 15% who are unable to be helped by the Arp Infant Respirator. The analysis included oxygen transfer studies and hemolysis studies. The oxygenator was able to transfer as much as 140cc0₂/min/m² at a flow rate of 300 ml/min with flow augmentation. Inlet oxygen saturation 1vas between 25-35%. Both the oxygenator and the ventricle type blood pump caused only very low levels of hemolysis. The pump showed a net increase of 54 mg hemoglobin/100 ml plasma after 5 days of continuous running at a flow rate of 200 ml/min. The complete extracorporeal circuit showed a net increase of only 61 mg hemoglobin/100 ml plasma. From this study, it is believed that this extracorporeal circuit can ,supply oxygen (140 cc0₂/min/m²) to a patient over an extended period of total or partial cardiopulmonary by-pass (at least 5 days) without significant levels of hemolysis (61 mg% after 5 days).iv, 62 leavesapplication/pdfenIn CopyrightLD5655.V855 1973.L48Thesis