Rowson, StevenCampolettano, Eamon T.Duma, Stefan M.Stemper, Brian D.Shah, Alok S.Harezlak, JaroslawRiggen, Larry D.Mihalik, Jason P.Guskiewicz, Kevin M.Giza, Christopher C.Brooks, M. AlisonCameron, Kenneth L.McAllister, Thomas W.Broglio, Steven P.McCrea, Michael A.2021-10-112021-10-112019-10-010090-696410.1007/s10439-019-02329-7 (PII)http://hdl.handle.net/10919/105223Researchers have been collecting head impact data from instrumented football players to characterize the biomechanics of concussion for the past 15 years, yet the link between biomechanical input and clinical outcome is still not well understood. We have previously shown that even though concussive biomechanics might be unremarkable in large datasets of head impacts, the impacts causing injury are of high magnitude for the concussed individuals relative to their impact history. This finding suggests a need to account for differences in tolerance at the individual level. In this study, we identified control subjects for our concussed subjects who demonstrated traits we believed were correlated to factors thought to affect injury tolerance, including height, mass, age, race, and concussion history. A total of 502 college football players were instrumented with helmet-mounted accelerometer arrays and provided complete baseline assessment data, 44 of which sustained a total of 49 concussion. Biomechanical measures quantifying impact frequency and acceleration magnitude were compared between groups. On average, we found that concussed subjects experienced 93.8 more head impacts (p = 0.0031), 10.2 more high magnitude impacts (p = 0.0157), and 1.9 × greater risk-weighted exposure (p = 0.0175) than their physically matched controls. This finding provides further evidence that head impact data need to be considered at the individual level and that cohort wide assessments may be of little value in the context of concussion.Pages 2048-20569 page(s)application/pdfenCreative Commons Attribution 4.0 InternationalEngineering, BiomedicalEngineeringBiomechanicsImpactBrain injuryThresholdFootballSensorsCOLLEGIATE FOOTBALL PLAYERSHIGH-SCHOOLIMPACT EXPOSUREINJURYBIOMECHANICSKINEMATICSMAGNITUDELOCATIONRISKBiomechanicsBrain injuryFootballImpactSensorsThreshold09 Engineering11 Medical and Health SciencesBiomedical EngineeringHeadHumansBrain ConcussionHead Protective DevicesAccelerationUniversitiesFootballAdolescentAdultMaleYoung AdultAthletesAccelerometryBiomechanical PhenomenaArticle - Refereed2021-10-11https://doi.org/10.1007/s10439-019-02329-74710Rowson, Steven [0000-0002-3227-0596]313423361573-9686