2016-08-242016-08-241989-09-05http://hdl.handle.net/10919/72341A method is provided for detecting the presence of C. difficile toxin A. Stool or other appropriate specimen is contacted with a reagent containing an available non-reducing galactose-alpha-1-3-galactosyl structure, which is a specific receptor for toxin A. The reagent may be intact cells, cell membranes, membrane fractions containing the toxin A receptor structure, glycoconjugates, as well as the purified toxin A receptor per se. Binding of toxin A is determined by conventional assay techniques. The method may also be used to isolate and purify toxin A. Conversely, immobilized toxin A is used to detect, isolate, or purify biological materials of interest containing the receptor structure.application/pdfen-USPatenthttp://pimg-fpiw.uspto.gov/fdd/52/638/048/0.pdf6828404435/7.25435/7.32435/7.92435/34435/39435/803435/842436/520436/534436/829530/413530/825G01N33/56911Y10S435/803Y10S435/842Y10S436/829Y10S530/8254863852