Behzadinasab, SaeedWilliams, Myra D.Falkinham, Joseph O.Ducker, William A.2023-05-262023-05-262023-05-17Behzadinasab, S.; Williams, M.D.; Falkinham, J.O., III; Ducker, W.A. Facile Implementation of Antimicrobial Coatings through Adhesive Films (Wraps) Demonstrated with Cuprous Oxide Coatings. Antibiotics 2023, 12, 920.http://hdl.handle.net/10919/115213Antimicrobial coatings have a finite lifetime because of wear, depletion of the active ingredient, or surface contamination that produces a barrier between the pathogen and the active ingredient. The limited lifetime means that facile replacement is important. Here, we describe a generic method for rapidly applying and reapplying antimicrobial coatings to common-touch surfaces. The method is to deposit an antimicrobial coating on a generic adhesive film (wrap), and then to attach that modified wrap to the common-touch surface. In this scenario, the adhesion of the wrap and antimicrobial efficacy are separated and can be optimized independently. We demonstrate the fabrication of two antimicrobial wraps, both using cuprous oxide (Cu₂O) as the active ingredient. The first uses polyurethane (PU) as the polymeric binder and the second uses polydopamine (PDA). Our antimicrobial PU/Cu₂O and PDA/Cu₂O wraps, respectively, kill &gt;99.98% and &gt;99.82% of the human pathogen, <i>P. aeruginosa,</i> in only 10 min, and each of them kill &gt;99.99% of the bacterium in 20 min. These antimicrobial wraps can be removed and replaced on the same object in &lt;1 min with no tools. Wraps are already frequently used by consumers to coat drawers or cars for aesthetic or protective purposes.application/pdfenCreative Commons Attribution 4.0 Internationalantimicrobialantibacterialwrapcoppercuprous oxideCu2OcoatingbacteriapolydopaminepolyurethaneArticle - Refereed2023-05-26https://doi.org/10.3390/antibiotics12050920