Abel, William F.Kesar, VarunWasserman, Reid D.Kumar, ManojPatel, VishalYeaton, PaulKesar, Vivek2024-07-262024-07-262024-02-142691-171XPMC11093900JPR312052 (PII)https://hdl.handle.net/10919/120704Pancreatitis is a condition much more commonly found in adults, but when diagnosed in the pediatric population, is often due to medications, congenital pathology, and critical illness. This patient had previously undergone treatment with 6-mercaptopurine and presented with pancreatitis that eventually worsened to a walled-off necrotic collection with paracolic extensions reaching the pelvis. Given clinical worsening with development of shock, procedural options for source control were weighed with gastroenterology, pediatric surgery, and interventional radiology, before pancreatic necrosectomy was determined to be the treatment of choice, given the adjacency of the collection to the stomach. A total of three separate endoscopic pancreatic necrosectomy procedures were performed and the patient s clinical status improved greatly, with vast improvement later seen on outpatient imaging. This successful treatment course argues for the efficacy of pancreatic necrosectomy even in very large walled off collections, and most importantly, lead to a positive outcome in this young patient.Pages 175-177application/pdfenCreative Commons Attribution 4.0 Internationalcollectionnecrosectomypancreatitiswalled‐off necrosisArticle - Refereedhttps://doi.org/10.1002/jpr3.1205252Kesar, Varun [0000-0002-2422-0249]Yeaton, Paul [0000-0002-1872-7377]387561102691-171X