2016-08-242016-08-241999-12-14http://hdl.handle.net/10919/72404The present invention relates to 2-debenzoyl-2-acyl taxol derivatives, analogues thereof and methods for making same. Compounds of the present invention include compounds having the general formula: ##STR1## wherein R.sub.1 is an alkyl or substituted alkyl; R.sub.2 is selected from the group consisting of H and C(O)R.sub.a ; R.sub.3 is selected from the group consisting of H, protecting groups, R.sub.b, and C(O)R.sub.b ; R.sub.4 is selected from the group consisting of H and C(O)R.sub.c, and wherein R.sub.a, R.sub.b, and R.sub.c are independently selected from the group consisting of alkyls, substituted alkyls, alkenyls, alkynyls, aryls, and substituted aryls; provided that R.sub.a is other than phenyl and 3-hydroxyphenyl.application/pdfen-USPatenthttp://pimg-fpiw.uspto.gov/fdd/23/020/060/0.pdf8950590549/510C07D405/12C07D305/14C07D409/12C07F7/1856Y02P20/556002023