Over-expressing homologous antigen vaccine and a method of making the same

2016-08-242016-08-242000-11-21http://hdl.handle.net/10919/72428This invention relates to an over-expressing homologous antigen vaccine, a method of producing the same, and use of the vaccine for prophylaxis or treatment of vertebrates at risk of or suffering from disease caused by a pathogenic micro-organism. The vaccine is an attenuated or avirulent pathogenic micro-organism that over-expresses at least one homologous antigen encoded by at least one gene derived from the pathogenic micro-organism, and may also express a heterologous antigen.application/pdfen-USOver-expressing homologous antigen vaccine and a method of making the samePatenthttp://pimg-fpiw.uspto.gov/fdd/20/499/061/0.pdf9091521424/252.1424/184.1424/200.1424/234.1424/248.1424/261.1435/69.1435/69.3435/243435/252.3435/320.1A61K39/00A61K2039/522C07K14/23C12N15/746149920