Flynn, Allison2014-03-142014-03-141994-06-05etd-03022010-020016http://hdl.handle.net/10919/41305<p>Since the discovery that cis-diamminedichloroplatinum (II) possessed great antitumor properties, researchers have been synthesizing and screening metal coordination complexes for their potential anti-tumor activity. Hundreds of compounds have been tested, and few compounds possessed anti-tumor activity. This paper examines how the physical and chemical properties of complexes of the platinum group metals affect their toxicity and anti-tumor activity.</p>x, 62 leavesBTDapplication/pdfenIn CopyrightLD5655.V851 1994.F596Antineoplastic agentsPlatinum groupTransition metals as anti-tumoral agents: some structure-function relationships of the platinum group metalsMaster's projecthttp://scholar.lib.vt.edu/theses/available/etd-03022010-020016/