Kim, Seo HyunSoliman, YoussefChitnavis, Vikas N.Chitnavis, Maithili V.2023-03-272023-03-272023-03-23Seo Hyun Kim, Youssef Soliman, Vikas N. Chitnavis, and Maithili V. Chitnavis, “Helicobacter Pylori-Negative MALT Lymphoma: A Series of Two Cases Presenting with Life-Threatening Upper Gastrointestinal Bleeding,” Case Reports in Gastrointestinal Medicine, vol. 2023, Article ID 8244696, 4 pages, 2023. doi:10.1155/2023/8244696http://hdl.handle.net/10919/114179Mucosa-associated lymphoid tissue (MALT) lymphoma is a common cause of gastric lymphoma. Although most cases are associated with an H. pylori infection, approximately 10% are H. pylori-negative. Patients with gastric MALT lymphoma are usually asymptomatic or present with nonspecific symptoms such as abdominal pain, dyspepsia, weight loss, and occult gastrointestinal bleeding. In this report, we describe two patients with H. pylori-negative MALT lymphoma who both presented with acute upper gastrointestinal bleeding that led to hemodynamic instability. After resuscitation, emergent endoscopy was performed. Both patients had the t (11; 18) (q21; q21) translocation, which prompted direct treatment by radiotherapy.application/pdfenCreative Commons Attribution 4.0 InternationalArticle - Refereed2023-03-26Copyright © 2023 Seo Hyun Kim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.https://doi.org/10.1155/2023/8244696