Chung, Michael H.Silverman, Rachel A.Beck, Ingrid A.Yatich, NellyDross, SandraMcKernan-Mullin, JenniferBii, StephenTapia, KennethStern, Joshua A.Chohan, BhavnaSakr, Samah R.Kiarie, James N.Frenkel, Lisa M.2022-01-132022-01-132016-06-190269-9370http://hdl.handle.net/10919/107613Antiretroviral-naïve adults initiating antiretroviral therapy in Nairobi, Kenya were tested for HIV-1 drug resistance at codons K103N, Y181C, G190A, M184V, and K65R using an oligonucleotide ligation assay. Prevalence of pretreatment drug resistance increased from 3.89% in 2006 to 10.93% in 2014 (P < 0.001), and 95% of those with resistance had at least one nonnucleoside reverse transcriptase inhibitor mutation. Resistance to tenofovir (K65R) was found in 2014 but not in 2006.Pages 1680-16824 page(s)application/pdfenIn CopyrightImmunologyInfectious DiseasesVirologyOLIGONUCLEOTIDE LIGATION ASSAYSUB-SAHARAN AFRICATYPE-1INDIVIDUALSINFECTIONROLLOUT06 Biological Sciences11 Medical and Health Sciences17 Psychology and Cognitive SciencesVirologyHumansHIV-1HIV InfectionsAnti-HIV AgentsPrevalenceDrug Resistance, ViralMutation, MissenseAdultKenyaFemaleMaleGenotyping TechniquesArticle - Refereed2022-01-13https://doi.org/10.1097/QAD.00000000000011103010Silverman, Rachel [0000-0003-3082-9664]270583531473-5571