Browsing by Author "Adams, D. A."

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    Charge State of the Globular Histone Core Controls Stability of the Nucleosome
    Fenley, Andrew T.; Adams, D. A.; Onufriev, Alexey V. (CELL PRESS, 2010-09-01)
    Presented here is a quantitative model of the wrapping and unwrapping of the DNA around the histone core of the nucleosome that suggests a mechanism by which this transition can be controlled: alteration of the charge state of the globular histone core. The mechanism is relevant to several classes of posttranslational modifications such as histone acetylation and phosphorylation; several specific scenarios consistent with recent in vivo experiments are considered. The model integrates a description based on an idealized geometry with one based on the atomistic structure of the nucleosome, and the model consistently accounts for both the electrostatic and nonelectrostatic contributions to the nucleosome free energy. Under physiological conditions, isolated nucleosomes are predicted to be very stable (38 +/- 7 kcal/mol). However, a decrease in the charge of the globular histone core by one unit charge, for example due to acetylation of a single lysine residue, can lead to a significant decrease in the strength of association with its DNA. In contrast to the globular histone core, comparable changes in the charge state of the histone tail regions have relatively little effect on the nucleosome's stability. The combination of high stability and sensitivity explains how the nucleosome is able to satisfy the seemingly contradictory requirements for thermodynamic stability while allowing quick access to its DNA informational content when needed by specific cellular processes such as transcription.
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    Coarsening of "clouds" and dynamic scaling in a far-from-equilibrium model system
    Adams, D. A.; Schmittmann, Beate; Zia, Royce K. P. (American Physical Society, 2007-04)
    A two-dimensional lattice gas of two species, driven in opposite directions by an external force, undergoes a jamming transition if the filling fraction is sufficiently high. Using Monte Carlo simulations, we investigate the growth of these jams ('' clouds ''), as the system approaches a nonequilibrium steady state from a disordered initial state. We monitor the dynamic structure factor S(k(x),k(y);t) and find that the k(x)=0 component exhibits dynamic scaling, of the form S(0,k(y);t)=t(beta)S(k(y)t(alpha)). Over a significant range of times, we observe excellent data collapse with alpha=1/2 and beta=1. The effects of varying filling fraction and driving force are discussed.
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    Deep Underground Neutrino Experiment (DUNE) Near Detector Conceptual Design Report
    Abud, A. Abed; Abi, B.; Acciarri, R.; Acero, M. A.; Adamov, G.; Adams, D. A.; Adinolfi, M.; Aduszkiewicz, A.; Ahmad, Z.; Ahmed, J.; Alion, T.; Monsalve, S. Alonso; Alrashed, M.; Alt, C.; Alton, A.; Amedo, P.; Anderson, J.; Andreopoulos, C.; Andrews, M. P.; Andrianala, F.; Andringa, S.; Anfimov, N.; Ankowski, A.; Antonova, M.; Antusch, S.; Aranda Fernandez, A.; Ariga, A.; Arnold, L. O.; Arroyave, M. A.; Asaadi, J.; Aurisano, A.; Aushev, V.; Autiero, D.; Ayala-Torres, M.; Azfar, F.; Back, A.; Back, Henning Olling; Back, J. J.; Backhouse, C.; Baesso, P.; Bagaturia, I.; Bagby, L.; Balasubramanian, S.; Baldi, P.; Baller, B.; Bambah, B.; Barao, F.; Barenboim, G.; Barker, G. J.; Barkhouse, W.; Barnes, C.; Barr, G.; Monarca, J. Barranco; Barros, N.; Barrow, J. L.; Basharina-Freshville, A.; Bashyal, A.; Basque, V.; Belchior, E.; Battat, J. B. R.; Battisti, F.; Bay, F.; Alba, J. L. Bazo; Beacom, J. F.; Bechetoille, E.; Behera, B.; Bellantoni, L.; Bellettini, G.; Bellini, V.; Beltramello, O.; Belver, D.; Benekos, N.; Neves, F. Bento; Berkman, S.; Bernardini, P.; Berner, R. M.; Berns, H.; Bertolucci, S.; Betancourt, M.; Rodríguez, A. Betancur; Bhattacharjee, M.; Bhuller, S.; Bhuyan, B.; Biagi, S.; Bian, J.; Biassoni, M.; Biery, K.; Bilki, B.; Bishai, M.; Bitadze, A.; Blake, A.; Blaszczyk, F. D. M.; Blazey, G. C.; Blucher, E.; Boissevain, J. G.; Bolognesi, S.; Bolton, T.; Bomben, L.; Bonesini, M.; Bongrand, M.; Bonini, F.; Booth, A.; Booth, C.; Bordoni, S.; Borkum, A.; Boschi, T.; Bostan, N.; Bour, P.; Bourgeois, C.; Boyd, S. B.; Boyden, D.; Bracinik, J.; Braga, D.; Brailsford, D.; Brandt, A.; Bremer, J.; Brew, C.; Brianne, E.; Brice, S. J.; Brizzolari, C.; Bromberg, C.; Brooijmans, G.; Brooke, J.; Bross, A.; Brunetti, G.; Brunetti, M.; Buchanan, N.; Budd, H.; Cagnoli, I.; Caiulo, D.; Calafiura, P.; Calcutt, J.; Calin, M.; Calvez, S.; Calvo, E.; Caminata, A.; Campanelli, M.; Cankocak, K.; Caratelli, D.; Carini, G.; Carlus, B.; Carniti, P.; Terrazas, I. Caro; Carranza, H.; Carroll, T.; Forero, J. F. Castaño; Castillo, A.; Castromonte, C.; CatanoMur, E.; Cattadori, C.; Cavalier, F.; Cavanna, F.; Centro, S.; Cerati, G.; Cervelli, A.; Cervera Villanueva, A.; Chalifour, M.; Chappell, A.; Chardonnet, E.; Charitonidis, N.; Chatterjee, A.; Chattopadhyay, S.; Chen, H.; Chen, M.; Chen, Y.; Chen, Z.; Cherdack, D.; Chi, C.; Childress, S.; Chiriacescu, A.; Chisnall, G.; Cho, K.; Choate, S.; Chokheli, D.; Choubey, S.; Christensen, A.; Christian, D.; Christodoulou, G.; Chukanov, A.; Church, E.; Cicero, V.; Clarke, P.; Coan, T. E.; Cocco, A. G.; Coelho, J. A. B.; Conley, E.; Conley, R.; Conrad, Janet M.; Convery, M.; Copello, S.; Corwin, L.; Cremaldi, L.; Cremonesi, L.; Crespo-Anadon, J. I.; Cristaldo, E.; Cross, R.; Cudd, A.; Cuesta, C.; Cui, Y.; Cussans, D.; Dabrowski, M.; Dalager, O.; Motta, H. da; Peres, L. Da Silva; David, C.; David, Q.; Davies, G. S.; Davini, S.; Dawson, J.; De, K.; Almeida, R. M. De; Debbins, P.; Bonis, I. De; Decowski, M. P.; Gouvea, A. D.; Holanda, P. C. De; Astiz, I. L. De Icaza; Deisting, A.; Jong, P. De; Delbart, A.; Delepine, D.; Delgado, M.; Dell’Acqua, A.; DeLurgio, P.; Neto, J. R. T. de Mello; DeMuth, D. M.; Dennis, S.; Densham, C.; Deptuch, G. W.; De Roeck, A.; Romeri, V. De; Souza, G. De; Dharmapalan, R.; Diaz, F.; Diaz, J. S.; Domizio, S. Di; Giulio, L. Di; Ding, P.; Di Noto, Lea; Distefano, C.; Diurba, R.; Diwan, M.; Djurcic, Zelimir; Dokania, N.; Dolan, S.; Dolinski, M. J.; Domine, L.; Douglas, D.; Douillet, D.; Drake, G.; Drielsma, F.; Duchesneau, D.; Duffy, K.; Dunne, P.; Durkin, T.; Duyang, H.; Dvornikov, O.; Dwyer, D. A.; Dyshkant, A. S.; Eads, M.; Earle, A.; Edmunds, D.; Eisch, J.; Emberger, L.; Emery, S.; Ereditato, A.; Escobar, C. O.; Eurin, G.; Evans, J. J.; Ewart, E.; Ezeribe, A. C.; Fahey, K.; Falcone, A.; Farnese, C.; Farzan, Y.; Felix, J.; Silva, M. Fernandes Carneiro da; Fernandez-Martinez, Enrique; Menendez, P. Fernandez; Ferraro, F.; Fields, L.; Filthaut, F.; Fiorentini, A.; Fitzpatrick, R. S.; Flanagan, W.; Fleming, B.; Flight, R.; Forero, D. V.; Fowler, J.; Fox, W.; Franc, J.; Francis, K.; Franco, D.; Freeman, J.; Freestone, J.; Fried, J.; Friedland, A.; Fuess, S.; Furic, I.; Furmanski, A. P.; Gabrielli, A.; Gago, A.; Gallagher, H.; Gallas, A.; Gallego-Ros, A.; Gallice, N.; Galymov, V.; Gamberini, E.; Gamble, T.; Gandhi, R.; Gandrajula, R.; Gao, F.; Gao, S.; Garcia-Gamez, D.; García-Peris, M. Á.; Gardiner, S.; Gastler, D.; Ge, G.; Gelli, B.; Gendotti, A.; Gent, S.; Ghorbani-Moghaddam, Z.; Gibin, D.; Gil-Botella, I.; Gilligan, S.; Girerd, C.; Giri, A. K.; Gnani, D.; Gogota, O.; Gold, M.; Golapinni, S.; Gollwitzer, K.; Gomes, R. A.; Bermeo, L. V. Gomez; Fajardo, L. S. Gomez; Gonnella, F.; Gonzalez-Cuevas, J. A.; Gonzalez-Diaz, D.; Gonzalez-Lopez, M.; Goodman, M. C.; Goodwin, O.; Goswami, S.; Gotti, C.; Goudzovski, E.; Grace, C.; Graham, M.; Gran, R.; Granados, E.; Granger, P.; Grant, A.; Grant, C.; Gratieri, D.; Green, P.; Greenler, L.; Greer, J.; Griffith, W. C.; Groh, M.; Grudzinski, J.; Grzelak, K.; Gu, W.; Guarino, V.; Guenette, R.; Guerard, E.; Guerzoni, M.; Guglielmi, A.; Guo, B.; Guthikonda, K. K.; Gutierrez, R.; Guzowski, P.; Guzzo, M. M.; Gwon, S.; Habig, A.; Hadavand, H.; Haenni, R.; Hahn, A.; Haiston, J.; Hamacher-Baumann, P.; Hamernik, T.; Hamilton, P.; Han, J.; Harris, D. A.; Hartnell, J.; Harton, J.; Hasegawa, T.; Hasnip, C.; Hatcher, R.; Hatfield, K. W.; Hatzikoutelis, A.; Hayes, C.; Hazen, E.; Heavey, A.; Heeger, K. M.; Heise, J.; Hennessy, K.; Henry, S.; Morquecho, M. A. Hernandez; Herner, K.; Hertel, L.; Hewes, J.; Higuera, A.; Hill, T.; Hillier, S. J.; Himmel, A.; Hoff, J.; Hohl, C.; Holin, A.; Hoppe, E.; Horton-Smith, Glenn A.; Hostert, M.; Hourlier, A.; Howard, B.; Howell, R.; Huang, J.; Huang, J.; Hugon, J.; Iles, G.; Ilic, N.; Iliescu, A. M.; Illingworth, R.; Ingratta, G.; Ioannisian, A.; Isenhower, L.; Itay, R.; Izmaylov, A.; Jackson, S.; Jain, V.; James, E.; Jargowsky, B.; Jediny, F.; Jena, D.; Jeong, Y. S.; Jesús-Valls, C.; Ji, X.; Jiang, L.; Jiménez, S.; Jipa, A.; Johnson, R.; Johnston, N.; Jones, B.; Jones, S. B.; Judah, M.; Jung, C. K.; Junk, T.; Jwa, Y.; Kabirnezhad, M.; Kaboth, A.; Kadenko, I.; Kakorin, I.; Kamiya, F.; Kaneshige, N.; Karagiorgi, Georgia S.; Karaman, G.; Karcher, A.; Karolak, M.; Karyotakis, Y.; Kasai, S.; Kasetti, S. P.; Kashur, L.; Kazaryan, N.; Kearns, E.; Keener, P.; Kelly, K. J.; Kemp, E.; Kemularia, O.; Ketchum, W.; Kettell, S. H.; Khabibullin, M.; Khotjantsev, A.; Khvedelidze, A.; Kim, D.; King, B.; Kirby, B.; Kirby, M.; Klein, J.; Koehler, K.; Koerner, L. W.; Kohn, S.; Koller, P. P.; Kolupaeva, L.; Kordosky, M.; Kosc, T.; Kose, U.; Kostelecký, V. A.; Kothekar, K.; Krennrich, F.; Kreslo, I.; Kudenko, Y.; Kudryavtsev, V. A.; Kulagin, S.; Kumar, J.; Kumar, P.; Kumar, R.; Kunze, P.; Kurita, N.; Kuruppu, C.; Kus, V.; Kutter, T.; Lambert, A.; Land, B.; Lande, K.; Lane, C. E.; Lang, K.; Langford, T.; Larkin, J.; Lasorak, P.; Last, D.; Lastoria, C.; Laundrie, A.; Laurenti, G.; Lawrence, A.; Lazanu, I.; LaZur, R.; Le, T.; Leardini, S.; Learned, J.; Lebrun, P.; LeCompte, T.; Miotto, G. Lehmann; Lehnert, R.; Oliveira, M. A. Leigui de; Leitner, M.; Li, L.; Li, S. W.; Li, T.; Li, Y.; Liao, H.; Lin, C. S.; Lin, Q.; Lin, S.; Lister, A.; Littlejohn, B. R.; Liu, J.; Lockwitz, S.; Loew, T.; Lokajicek, M.; Lomidze, I.; Long, K.; Loo, K.; Lorca, D.; Lord, T.; LoSecco, J. M.; Louis, W. C.; Lu, X. G.; Luk, K. B.; Luo, X.; Lurkin, N.; Lux, T.; Luzio, V. P.; MacFarlane, D.; Machado, A. A.; Machado, P.; Macias, C. T.; Macier, J. R.; Maddalena, A.; Madera, A.; Madigan, P.; Magill, S.; Mahn, K.; Maio, A.; Major, A.; Maloney, J. A.; Mandrioli, G.; Mandujano, R. C.; Maneira, J.; Manenti, L.; Manly, S.; Mann, A.; Manolopoulos, K.; Plata, M. Manrique; Manyam, V. N.; Manzanillas, L.; Marchan, M.; Marchionni, A.; Marciano, W. J.; Marfatia, D.; Mariani, Camillo; Maricic, Jelena; Marie, R.; Marinho, F.; Marino, A. D.; Marsden, D.; Marshak, M.; Marshall, C. M.; Marshall, J.; Marteau, J.; Martin-Albo, J.; Martinez, N.; Martinez Caicedo, D. A.; Martynenko, S.; Mason, K.; Mastbaum, A.; Masud, M.; Matsuno, S.; Matthews, J.; Mauger, C.; Mauri, N.; Mavrokoridis, K.; Mawby, I.; Mazza, R.; Mazzacane, A.; Mazzucato, E.; McAskill, T.; McCluskey, E.; McConkey, N.; McFarland, K. S.; McGrew, C.; McNab, A.; Mefodiev, A.; Mehta, P.; Melas, P.; Mena, O.; Menary, S.; Mendez, H.; Méndez, D. P.; Menegolli, A.; Meng, G.; Messier, M. D.; Metcalf, W.; Mettler, T.; Mewes, M.; Meyer, H.; Miao, T.; Michna, G.; Miedema, T.; Migenda, J.; Mikola, V.; Milincic, R.; Miller, W.; Mills, J.; Milne, C.; Mineev, O.; Miranda, O. G.; Miryala, S.; Mishra, C. S.; Mishra, S. R.; Mislivec, A.; Mladenov, D.; Mocioiu, I.; Moffat, K.; Moggi, N.; Mohanta, R.; Mohayai, T. A.; Mokhov, N.; Molina, J.; Bueno, L. Molina; Montanari, A.; Montanari, C.; Montanari, D.; Montagna, E.; Zetina, L. M. Montano; Moon, J.; Mooney, M.; Moor, A. F.; Moreno, D.; Morris, C.; Mossey, C.; Motuk, E.; Moura, C. A.; Mousseau, J.; Mu, W.; Mualem, L.; Mueller, J.; Muether, M.; Mufson, S.; Muheim, F.; Muir, A.; Mulhearn, M.; Munford, D.; Muramatsu, H.; Murphy, S.; Musser, J.; Nachtman, J.; Nagu, S.; Nalbandyan, M.; Nandakumar, R.; Naples, D.; Narita, S.; Navas-Nicolás, D.; Navrer-Agasson, A.; Nayak, N.; Nebot-Guinot, M.; Negishi, K.; Nelson, J. K.; Nesbit, J.; Nessi, M.; Newbold, D.; Newcomer, M.; Newhart, D.; Newton, H.; Niccolo, M.; Nichol, R.; Nicolas-Arnaldos, F.; Nicoletta, M.; Niner, E.; Nishimura, K.; Norman, A.; Norrick, A.; Northrop, R.; Novella, P.; Nowak, J.; Oberling, M.; Ochoa-Ricoux, J. P.; Campo, A. Olivares Del; Olivier, A.; Olshevski, A.; Onel, Y.; Onishchuk, Y.; Ott, J.; Pagani, L.; Pakvasa, S.; Palacio, G.; Palamara, O.; Palestini, S.; Paley, J. M.; Pallavicini, M.; Palomares, C.; Palomino-Gallo, J. L.; Pantic, E.; Paolone, V.; Papadimitriou, V.; Papaleo, R.; Papanestis, A.; Paramesvaran, S.; Parke, S.; Parsa, Z.; Parvu, M.; Pascoli, S.; Pasqualini, L.; Pasternak, J.; Pater, J.; Patrick, C.; Patrizii, L.; Patterson, R. B.; Patton, S. J.; Patzak, T.; Paudel, A.; Paulos, B.; Paulucci, L.; Pavlovic, Z.; Pawloski, G.; Payne, D.; Pec, V.; Peeters, S. J. M.; Pennacchio, E.; Penzo, A.; Peres, O. L. G.; Perry, J.; Pershey, D.; Pessina, G.; Petrillo, G.; Petta, C.; Petti, R.; Piastra, F.; Pickering, L.; Pietropaolo, F.; Plunkett, R.; Poling, R.; Pons, X.; Poonthottathil, N.; Poppi, F.; Pordes, S.; Porter, J.; Potekhin, M.; Potenza, R.; Potukuchi, B. V. K. S.; Pozimski, J.; Pozzato, M.; Prakash, S.; Prakash, T.; Prince, S.; Pugnere, D.; Qian, X.; Bazetto, M. C. Queiroga; Raaf, J. L.; Radeka, V.; Rademacker, J.; Radics, B.; Rafique, A.; Raguzin, E.; Rai, M.; Rajaoalisoa, M.; Rakhno, I.; Rakotonandrasana, A.; Rakotondravohitra, L.; Ramachers, Y. A.; Rameika, R.; Delgado, M. A. Ramirez; Ramson, B.; Rappoldi, A.; Raselli, G. L.; Ratoff, P.; Raut, S.; Razakamiandra, R. F.; Real, J. S.; Rebel, B.; Reggiani-Guzzo, M.; Rehak, T.; Reichenbacher, J.; Reitzner, S. D.; Sfar, H. Rejeb; Renshaw, A. L.; Rescia, S.; Resnati, F.; Reynolds, A.; Riccio, C.; Riccobene, G.; Rice, L. C. J.; Ricol, J.; Rigamonti, A.; Rigaut, Y.; Rivera, D.; Rochester, L.; Roda, M.; Rodrigues, P.; Alonso, M. J. Rodriguez; Bonilla, E. Rodriguez; Rondon, J. Rodriguez; Rosauro-Alcaraz, S.; Rosenberg, M.; Rosier, P.; Roskovec, B.; Rossella, M.; Rout, J.; Roy, P.; Roy, S.; Rubbia, A.; Rubbia, C.; Rubio, F. C.; Russell, B.; Ruterbories, D.; Saakyan, R.; Sacerdoti, S.; Safford, T.; Sahay, R.; Sahu, N.; Sala, P.; Samios, N.; Samoylov, O.; Sanchez, Maria Cristina; Sanders, D. A.; Sankey, D.; Santana, S.; Santos-Maldonado, M.; Saoulidou, N.; Sapienza, P.; Sarasty, C.; Sarcevic, I.; Savage, G.; Savinov, V.; Scaramelli, A.; Scarff, A.; Scarpelli, A.; Schaffer, T.; Schellman, H.; Schlabach, P.; Schmitz, D.; Scholberg, K.; Schukraft, A.; Segreto, E.; Sensenig, J.; Seong, I.; Sergi, A.; Sgalaberna, D.; Shaevitz, Marjorie Hansen; Shafaq, S.; Shamma, M.; Sharankova, R.; Sharma, H. R.; Sharma, R.; Shaw, T.; Shepherd-Themistocleous, C.; Shin, S.; Shooltz, D.; Shrock, R.; Simard, L.; Simon, F.; Simos, N.; Sinclair, J.; Sinev, G.; Singh, J.; Singh, J.; Singh, V.; Sipos, R.; Sippach, F. W.; Sirri, G.; Sitraka, A.; Siyeon, K.; VIII, K. Skarpaas; Smith, A.; Smith, E.; Smith, P.; Smolik, J.; Smy, M.; Snider, E. L.; Snopok, P.; Nunes, M. Soares; Sobel, H.; Soderberg, M.; Salinas, C. J. Solano; Söldner-Rembold, S.; Soleti, S. R.; Solomey, N.; Solovov, V.; Sondheim, W. E.; Sorel, M.; Soto-Oton, J.; Sousa, A.; Soustruznik, K.; Spagliardi, F.; Spanu, M.; Spitz, Joshua; Spooner, N. J. C.; Spurgeon, K.; Staley, R.; Stancari, M.; Stanco, L.; Stanley, R.; Stein, R.; Steiner, H. M.; Stewart, J.; Stillwell, B.; Stock, J.; Stocker, F.; Stokes, T.; Strait, M.; Strauss, T.; Striganov, S.; Stuart, A.; Suarez, J. G.; Sullivan, H.; Summers, D.; Surdo, A.; Susic, V.; Suter, L.; Sutera, C. M.; Svoboda, R.; Szczerbinska, B.; Szelc, A. M.; Talaga, R.; Tanaka, H. A.; Oregui, B. Tapia; Tapper, A.; Tariq, S.; Tatar, E.; Tayloe, R.; Teklu, A. M.; Tenti, M.; Terao, K.; Ternes, C. A.; Terranova, F.; Testera, G.; Thea, A.; Thompson, J. L.; Thorn, C.; Timm, S. C.; Todd, J.; Tonazzo, A.; Torbunov, D.; Torti, M.; Tortola, M.; Tortorici, F.; Totani, D.; Toups, M.; Touramanis, C.; Tosi, N.; Travaglini, R.; Trevor, J.; Trilov, S.; Trzaska, W. H.; Tsai, Y. T.; Tsamalaidze, Z.; Tsang, K. V.; Tsverava, N.; Tufanli, S.; Tull, C.; Tyley, E.; Tzanov, M.; Uchida, M. A.; Urheim, J.; Usher, T.; Uzunyan, S.; Vagins, M. R.; Vahle, P.; Valdiviesso, G. A.; Valencia, E.; Valerio, P.; Vallari, Z.; Valle, J. W. F.; Vallecorsa, S.; Berg, R. Van; Van de Water, R. G.; Varanini, F.; Vargas, D.; Varner, G.; Vasel, J.; Vasina, S.; Vasseur, G.; Vaughan, N.; Vaziri, K.; Ventura, S.; Verdugo, A.; Vergani, S.; Vermeulen, M. A.; Verzocchi, M.; Vicenzi, M.; Souza, H. Vieira de; Vignoli, C.; Vilela, C.; Viren, B.; Vrba, T.; Wachala, T.; Waldron, A. V.; Wallbank, M.; Wang, H.; Wang, J.; Wang, L.; Wang, M. H. L. S.; Wang, Y.; Wang, Y.; Warburton, K.; Warner, D.; Wascko, M. O.; Waters, D.; Watson, A.; Weatherly, P.; Weber, A.; Weber, M.; Wei, H.; Weinstein, A.; Wenman, D.; Wetstein, M.; White, A.; Whitehead, L.; Whittington, D.; Wilking, M. J.; Wilkinson, C.; Williams, Z.; Wilson, F.; Wilson, R. J.; Wolcott, J.; Wongjirad, T.; Wood, A.; Wood, K.; Worcester, E.; Worcester, M.; Wret, C.; Wu, W.; Wu, W.; Xiao, Y.; Yandel, E.; Yang, G.; Yang, K.; Yang, S.; Yang, T.; Yankelevich, A.; Yershov, N.; Yonehara, K.; Young, T.; Yu, B.; Yu, H.; Yu, J.; Yuan, W.; Zaki, R.; Zalesak, J.; Zambelli, L.; Zamorano, B.; Zani, A.; Zazueta, L.; Zeit, G.; Zeller, Geralyn P.; Zennamo, J.; Zeug, K.; Zhang, C.; Zhao, M.; Zhivun, E.; Zhu, G.; Zilberman, P.; Zimmerman, E. D.; Zito, M.; Zucchelli, S.; Zuklin, J.; Zutshi, V.; Zwaska, R.; On behalf of the DUNE Collaboration (MDPI, 2021-09-29)
    The Deep Underground Neutrino Experiment (DUNE) is an international, world-class experiment aimed at exploring fundamental questions about the universe that are at the forefront of astrophysics and particle physics research. DUNE will study questions pertaining to the preponderance of matter over antimatter in the early universe, the dynamics of supernovae, the subtleties of neutrino interaction physics, and a number of beyond the Standard Model topics accessible in a powerful neutrino beam. A critical component of the DUNE physics program involves the study of changes in a powerful beam of neutrinos, i.e., neutrino oscillations, as the neutrinos propagate a long distance. The experiment consists of a near detector, sited close to the source of the beam, and a far detector, sited along the beam at a large distance. This document, the DUNE Near Detector Conceptual Design Report (CDR), describes the design of the DUNE near detector and the science program that drives the design and technology choices. The goals and requirements underlying the design, along with projected performance are given. It serves as a starting point for a more detailed design that will be described in future documents.
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    The Long-Baseline Neutrino Experiment: Exploring Fundamental Symmetries of the Universe
    Collaboration, LBNE; Adams, C.; Adams, D. A.; Akiri, T.; Alion, T.; Anderson, K.; Andreopoulos, C.; Andrews, M.; Anghel, I.; Anjos, JCCD; Antonello, M.; Arrieta-Diaz, E.; Artuso, M.; Asaadi, J.; Bai, X.; Baibussinov, B.; Baird, M.; Balantekin, A. B.; Baller, B.; Baptista, B.; Barker, D.; Barker, G.; Barletta, W. A.; Barr, G.; Bartoszek, L.; Bashyal, A.; Bass, M.; Bellini, V.; Benetti, P. A.; Berger, B. E.; Bergevin, M.; Berman, E.; Berns, H. G.; Bernstein, A.; Bernstein, R.; Bhandari, B.; Bhatnagar, V.; Bhuyan, B.; Bian, J.; Bishai, M.; Blake, A.; Blaszczyk, F.; Blaufuss, E.; Bleakley, B.; Blucher, E.; Blusk, S.; Bocean, V.; Boffelli, F.; Boissevain, J. G.; Bolton, T.; Bonesini, M.; Boyd, S.; Brandt, A.; Breedon, R.; Bromberg, C.; Brown, R.; Brunetti, G.; Buchanan, N.; Bugg, B.; Busenitz, J.; Calligarich, E.; Camilleri, Leslie; Carminati, G.; Carr, Rachel E.; Castromonte, C.; Cavanna, F.; Centro, S.; Chen, A.; Chen, H.; Chen, K.; Cherdack, D.; Chi, C. Y.; Childress, S.; Choudhary, B. C.; Christodoulou, G.; Christofferson, C. A.; Church, E.; Cline, D.; Coan, T.; Cocco, A.; Coelho, J.; Coleman, S.; Conrad, Janet M.; Convery, M.; Corey, R.; Corwin, L.; Cranshaw, J.; Cronin-Hennessy, D.; Curioni, A.; Motta, H. D.; Davenne, T.; Davies, G. S.; Dazeley, S.; De, K.; Gouvea, A. D.; Jong, J K. D.; Demuth, D.; Densham, C.; Diwan, M.; Djurcic, Zelimir; Dolfini, R.; Dolph, J.; Drake, G.; Dye, S.; Dyuang, H.; Edmunds, D.; Elliott, S.; Elnimr, M.; Eno, S.; Enomoto, S.; Escobar, C. O.; Evans, J.; Falcone, A.; Falk, L.; Farbin, A.; Farnese, C.; Fava, A.; Felde, J.; Fernandes, S.; Ferroni, F.; Feyzi, F.; Fields, L.; Finch, A.; Fitton, M.; Fleming, B.; Fowler, J.; Fox, W.; Friedland, A.; Fuess, S.; Fujikawa, B. K.; Gallagher, H.; Gandhi, R.; Garvey, G. T.; Gehman, V. M.; Geronimo, G. D.; Gibin, D.; Gill, R.; Gomes, R. A.; Goodman, M. C.; Goon, J.; Graf, N.; Graham, M.; Gran, R.; Grant, C.; Grant, N.; Greenlee, H.; Greenler, L.; Grullon, S.; Guardincerri, E.; Guarino, V.; Guarnaccia, E.; Guedes, G. P.; Guenette, R.; Guglielmi, A.; Guzzo, M. M.; Habig, A. T.; Hackenburg, R. W.; Hadavand, H.; Hahn, A.; Haigh, M.; Haines, T.; Handler, T.; Hans, S.; Hartnell, J.; Harton, J.; Hatcher, R.; Hatzikoutelis, A.; Hays, S.; Hazen, E.; Headley, M.; Heavey, A.; Heeger, K.; Heise, J.; Hellauer, R.; Hewes, J.; Himmel, A.; Hogan, M.; Holanda, P.; Holin, A.; Horton-Smith, Glenn A.; Howell, J.; Hurh, P.; Huston, J.; Hylen, J.; Imlay, R.; Insler, J.; Introzzi, G.; Isvan, Z.; Jackson, C.; Jacobsen, J.; Jaffe, D. E.; James, C.; Jen, C. M.; Johnson, M.; Johnson, R.; Johnson, S.; Johnston, W.; Johnstone, J.; Jones, B. J. P.; Jostlein, H.; Junk, T.; Kadel, R.; Kaess, K.; Karagiorgi, Georgia S.; Kaspar, J.; Katori, T.; Kayser, B.; Kearns, E.; Keener, P.; Kemp, E.; Kettell, S. H.; Kirby, M.; Klein, J.; Koizumi, G.; Kopp, S.; Kormos, L.; Kropp, W.; Kudryavtsev, V. A.; Kumar, A.; Kumar, J.; Kutter, T.; Zia, F. L.; Lande, K.; Lane, C.; Lang, K.; Lanni, F.; Lanza, R.; Latorre, T.; Learned, J.; Lee, D.; Lee, K.; Li, Q.; Li, S.; Li, Y.; Li, Z.; Libo, J.; Linden, S.; Ling, J.; Link, Jonathan M.; Littenberg, L.; Liu, H.; Liu, Q.; Liu, T.; Losecco, J.; Louis, W.; Lundberg, B.; Lundin, T.; Lundy, J.; Machado, A. A.; Maesano, C.; Magill, S.; Mahler, G.; Malon, D.; Malys, S.; Mammoliti, F.; Mandal, S. K.; Mann, A.; Mantsch, P.; Marchionni, A.; Marciano, W. J.; Mariani, Camillo; Maricic, Jelena; Marino, A.; Marshak, M.; Marshall, J.; Matsuno, S.; Mauger, C.; Mavrokoridis, K.; Mayer, N.; McCauley, N.; McCluskey, E.; McDonald, K.; McFarland, K. S.; McKee, D.; McKeown, R.; McTaggart, R.; Mehdiyev, R.; Mei, D.; Menegolli, A.; Meng, G.; Meng, Y.; Mertins, D.; Messier, M.; Metcalf, W.; Milincic, R.; Miller, W.; Mills, G.; Mishra, S. R.; Mokhov, N.; Montanari, C.; Montanari, D.; Moore, C.; Morfin, J.; Morgan, B.; Morse, W.; Moss, Z.; Moura, C. A.; Mufson, S.; Muller, D.; Musser, J.; Naples, D.; Napolitano, J.; Newcomer, M.; Nichol, R.; Nicholls, T.; Niner, E.; Norris, B.; Nowak, J.; O'Keeffe, H.; Oliveira, R.; Olson, T.; Page, B.; Pakvasa, S.; Palamara, O.; Paley, J.; Paolone, V.; Papadimitriou, V.; Park, S.; Parsa, Z.; Partyka, K.; Paulos, B.; Pavlovic, Z.; Peeters, S.; Perch, A.; Perkin, J. D.; Petti, R.; Petukhov, A.; Pietropaolo, F.; Plunkett, R.; Polly, C. C.; Pordes, S.; Potekhin, M.; Potenza, R.; Prakash, A.; Prokofiev, O.; Qian, X.; Raaf, J. L.; Radeka, V.; Rakhno, I.; Ramachers, Y. A.; Rameika, R.; Ramsey, J.; Rappoldi, A.; Raselli, G. L.; Ratoff, P.; Ravindra, S.; Rebel, B.; Reichenbacher, J.; Reitzner, D.; Rescia, S.; Richardson, M.; Rielage, K.; Riesselmann, K.; Robinson, M.; Rochester, L.; Ronquest, M.; Rosen, M.; Rossella, M.; Rubbia, C.; Rucinski, R.; Sahijpal, S.; Sahoo, H.; Sala, P.; Salmiera, D.; Samios, N.; Sanchez, Maria Cristina; Scaramelli, A.; Schellman, H.; Schmitt, R.; Schmitz, D.; Schneps, J.; Scholberg, K.; Segreto, E.; Seibert, S.; Sexton-Kennedy, L.; Shaevitz, Marjorie Hansen; Shanahan, P.; Sharma, R.; Shaw, T.; Simos, N.; Singh, V.; Sinnis, G.; Sippach, W.; Skwarnicki, T.; Smy, M.; Sobel, H.; Soderberg, M.; Sondericker, J.; Sondheim, W.; Sousa, A.; Spooner, N. J. C.; Stancari, M.; Stancu, Ion; Stefan, D.; Stefanik, A.; Stewart, J.; Stone, S.; Strait, J.; Strait, M.; Striganov, S.; Sullivan, G.; Sun, Y.; Suter, L.; Svenson, A.; Svoboda, R.; Szczerbinska, B.; Szelc, A.; Szydagis, M.; Söldner-Rembold, S.; Talaga, R.; Tamsett, M.; Tariq, S.; Tayloe, R.; Taylor, C.; Taylor, D.; Teymourian, A.; Themann, H.; Thiesse, M.; Thomas, J.; Thompson, L. F.; Thomson, M.; Thorn, C.; Thorpe, M.; Tian, X.; Tiedt, D.; Toki, W.; Tolich, N.; Torti, M.; Toups, M.; Touramanis, C.; Tripathi, M.; Tropin, I.; Tsai, Y. T.; Tull, C.; Tzanov, M.; Urheim, J.; Usman, S.; Vagins, M. R.; Valdiviesso, G. A.; Berg, R. V.; Water, R. V. D.; Gemmeren, P. V.; Varanini, F.; Varner, G.; Vaziri, K.; Velev, G.; Ventura, S.; Vignoli, C.; Viren, B.; Wahl, D.; Waldron, A.; Walter, C. W.; Wang, H.; Wang, W.; Warburton, K.; Warner, D.; Wasserman, R.; Watson, B.; Weber, A.; Wei, W.; Wells, D.; Wetstein, M.; White, A.; White, H.; Whitehead, L.; Whittington, D.; Willhite, J.; Wilson, R. J.; Winslow, L.; Wood, K.; Worcester, E.; Worcester, M.; Xin, T.; Yarritu, K.; Ye, J.; Yeh, M.; Yu, B.; Yu, J.; Yuan, T.; Zani, A.; Zeller, Geralyn P.; Zhang, C.; Zimmerman, E. D.; Zwaska, R. (2014-04-15)
    The preponderance of matter over antimatter in the early Universe, the dynamics of the supernova bursts that produced the heavy elements necessary for life and whether protons eventually decay --- these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our Universe, its current state and its eventual fate. The Long-Baseline Neutrino Experiment (LBNE) represents an extensively developed plan for a world-class experiment dedicated to addressing these questions. LBNE is conceived around three central components: (1) a new, high-intensity neutrino source generated from a megawatt-class proton accelerator at Fermi National Accelerator Laboratory, (2) a near neutrino detector just downstream of the source, and (3) a massive liquid argon time-projection chamber deployed as a far detector deep underground at the Sanford Underground Research Facility. This facility, located at the site of the former Homestake Mine in Lead, South Dakota, is approximately 1,300 km from the neutrino source at Fermilab -- a distance (baseline) that delivers optimal sensitivity to neutrino charge-parity symmetry violation and mass ordering effects. This ambitious yet cost-effective design incorporates scalability and flexibility and can accommodate a variety of upgrades and contributions. With its exceptional combination of experimental configuration, technical capabilities, and potential for transformative discoveries, LBNE promises to be a vital facility for the field of particle physics worldwide, providing physicists from around the globe with opportunities to collaborate in a twenty to thirty year program of exciting science. In this document we provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess.
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    Power spectra of the total occupancy in the totally asymmetric simple exclusion process
    Adams, D. A.; Zia, Royce K. P.; Schmittmann, Beate (American Physical Society, 2007-07-13)
    As a solvable and broadly applicable model system, the totally asymmetric exclusion process enjoys iconic status in the theory of nonequilibrium phase transitions. Here, we focus on the time dependence of the total number of particles on a 1-dimensional open lattice and its power spectrum. Using both Monte Carlo simulations and analytic methods, we explore its behavior in different characteristic regimes. In the maximal current phase and on the coexistence line (between high and low density phases), the power spectrum displays algebraic decay, with exponents -1.62 and -2.00, respectively. Deep within the high and low density phases, we find pronounced oscillations, which damp into power laws. This behavior can be understood in terms of driven biased diffusion with conserved noise in the bulk.