Browsing by Author "Greear, Emma L."

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    Glucocorticoid induced osteoporosis: Increased awareness as a management strategy for prevention of this complication in patients with systemic autoimmune rheumatic disease
    Bankole, Adegbenga; Greear, Emma L. (AVES Yayincilik, 2023-08)
    Background: It has been estimated that about 1% of the US population is treated with long-term glucocorticoids. High doses of glucocorticoids particularly those used by rheumatologists and others for systemic autoimmune rheumatic disease result in bone loss, causing glucocorticoid-induced osteoporosis and an increase in the risk of fractures. The increased risk is related to both the daily dose and the cumulative dose of the glucocorticoids. Despite the availability of effective preventative and treatment options, glucocorticoid-induced osteoporosis is often not mitigated with the use of these preventive therapies. The risk of glucocorticoid-induced osteoporosis often also goes underrecognized, because it occurs in a different group of patients compared to age-related osteoporosis. As a result, glucocorticoid-induced osteoporosis is not always treated until after fractures may have occurred. Our objective is to determine if a structured health-care provider’s educational intervention with intermittent educational updates would lead to improvement in the identification, evaluation, and prevention of glucocorticoid-induced osteoporosisin those patients at the highest risk of glucocorticoid-induced osteoporosis. Methods: In this single-center, prospective study, patients over 40 years of age, receiving a total cumulative dose of glucocorticoids of >5 g or a single dose of >30 mg of prednisone or its equivalent was enrolled. All providers attended an academic Journal Club, where the current American College of Rheumatology guidelines regarding glucocorticoid-induced osteoporosiswas reviewed. All providers received monthly reminders during academic meetings within the department. Results: There was a statistically significant improvement between pre- and post-educational data, with increasing use of glucocorticoid-induced osteoporosis preventive measures, which was sustained over the 12-month duration of the study. Conclusion: This research shows the importance of provider education as a means of disseminating information and improving the quality of patient care.
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    Kikuchi-Fujimoto Disease: A Differential for When It is Not Systemic Lupus Erythematosus
    Kazmi, Taskeen R.; Greear, Emma L.; Lavallee, Catherine A.; Stump, Michael S.; Bankole, Adegbenga A. (Hindawi, 2022-08-09)
    Kikuchi-Fujimoto disease (KFD) is a rare and benign disease process that is characterized by fever and lymphadenopathy that was first described in young Japanese women in the early 1970s. Knowledge of KFD is important as it can often mimic other causes of lymphadenopathy including systemic lupus erythematosus (SLE) or malignancies, and this can lead to invasive diagnostic testing and even treatments that can be avoided. The etiology and exact mechanism by which KFD develops is not fully understood at this time, but is thought to be an immune response of T cells and histiocytes to viral or bacterial infections. We present a 35-year-old African-American woman who was referred to the rheumatology clinic by our colleagues in the breast clinic with new onset right axillary lymphadenopathy and abnormal serologic testing with the suspicion of SLE after a malignancy had been ruled out.