Browsing by Author "Kueneman, Jordan G."

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    A communal catalogue reveals Earth's multiscale microbial diversity
    Thompson, Luke R.; Sanders, Jon G.; McDonald, Daniel; Amir, Amnon; Ladau, Joshua; Locey, Kenneth J.; Prill, Robert J.; Tripathi, Anupriya; Gibbons, Sean M.; Ackermann, Gail; Navas-Molina, Jose A.; Janssen, Stefan; Kopylova, Evguenia; Vazquez-Baeza, Yoshiki; Gonzalez, Antonio; Morton, James T.; Mirarab, Siavash; Xu, Zhenjiang Zech; Jiang, Lingjing; Haroon, Mohamed F.; Kanbar, Jad; Zhu, Qiyun; Song, Se Jin; Kosciolek, Tomasz; Bokulich, Nicholas A.; Lefler, Joshua; Brislawn, Colin J.; Humphrey, Gregory; Owens, Sarah M.; Hampton-Marcell, Jarrad; Berg-Lyons, Donna; McKenzie, Valerie; Fierer, Noah; Fuhrman, Jed A.; Clauset, Aaron; Stevens, Rick L.; Shade, Ashley; Pollard, Katherine S.; Goodwin, Kelly D.; Jansson, Janet K.; Gilbert, Jack A.; Knight, Rob; Rivera, Jose L. Agosto; Al-Moosawi, Lisa; Alverdy, John; Amato, Katherine R.; Andras, Jason; Angenent, Largus T.; Antonopoulos, Dionysios A.; Apprill, Amy; Armitage, David; Ballantine, Kate; Barta, Jiri; Baum, Julia K.; Berry, Allison; Bhatnagar, Ashish; Bhatnagar, Monica; Biddle, Jennifer F.; Bittner, Lucie; Boldgiv, Bazartseren; Bottos, Eric M.; Boyer, Donal M.; Braun, Josephine; Brazelton, William; Brearley, Francis Q.; Campbell, Alexandra H.; Caporaso, J. Gregory; Cardona, Cesar; Carroll, JoLynn; Cary, S. Craig; Casper, Brenda B.; Charles, Trevor C.; Chu, Haiyan; Claar, Danielle C.; Clark, Robert G.; Clayton, Jonathan B.; Clemente, Jose C.; Cochran, Alyssa; Coleman, Maureen L.; Collins, Gavin; Colwell, Rita R.; Contreras, Monica; Crary, Benjamin B.; Creer, Simon; Cristol, Daniel A.; Crump, Byron C.; Cui, Duoying; Daly, Sarah E.; Davalos, Liliana; Dawson, Russell D.; Defazio, Jennifer; Delsuc, Frederic; Dionisi, Hebe M.; Dominguez-Bello, Maria Gloria; Dowell, Robin; Dubinsky, Eric A.; Dunn, Peter O.; Ercolini, Danilo; Espinoza, Robert E.; Ezenwa, Vanessa; Fenner, Nathalie; Findlay, Helen S.; Fleming, Irma D.; Fogliano, Vincenzo; Forsman, Anna; Freeman, Chris; Friedman, Elliot S.; Galindo, Giancarlo; Garcia, Liza; Alexandra Garcia-Amado, Maria; Garshelis, David; Gasser, Robin B.; Gerdts, Gunnar; Gibson, Molly K.; Gifford, Isaac; Gill, Ryan T.; Giray, Tugrul; Gittel, Antje; Golyshin, Peter; Gong, Donglai; Grossart, Hans-Peter; Guyton, Kristina; Haig, Sarah-Jane; Hale, Vanessa; Hall, Ross Stephen; Hallam, Steven J.; Handley, Kim M.; Hasan, Nur A.; Haydon, Shane R.; Hickman, Jonathan E.; Hidalgo, Glida; Hofmockel, Kirsten S.; Hooker, Jeff; Hulth, Stefan; Hultman, Jenni; Hyde, Embriette; Ibanez-Alamo, Juan Diego; Jastrow, Julie D.; Jex, Aaron R.; Johnson, L. Scott; Johnston, Eric R.; Joseph, Stephen; Jurburg, Stephanie D.; Jurelevicius, Diogo; Karlsson, Anders; Karlsson, Roger; Kauppinen, Seth; Kellogg, Colleen T. E.; Kennedy, Suzanne J.; Kerkhof, Lee J.; King, Gary M.; Kling, George W.; Koehler, Anson V.; Krezalek, Monika; Kueneman, Jordan G.; Lamendella, Regina; Landon, Emily M.; Lane-deGraaf, Kelly; LaRoche, Julie; Larsen, Peter; Laverock, Bonnie; Lax, Simon; Lentino, Miguel; Levin, Iris I.; Liancourt, Pierre; Liang, Wenju; Linz, Alexandra M.; Lipson, David A.; Liu, Yongqin; Lladser, Manuel E.; Lozada, Mariana; Spirito, Catherine M.; MacCormack, Walter P.; MacRae-Crerar, Aurora; Magris, Magda; Martin-Platero, Antonio M.; Martin-Vivaldi, Manuel; Margarita Martinez, L.; Martinez-Bueno, Manuel; Marzinelli, Ezequiel M.; Mason, Olivia U.; Mayer, Gregory D.; McDevitt-Irwin, Jamie M.; McDonald, James E.; McGuire, Krista L.; McMahon, Katherine D.; McMinds, Ryan; Medina, Monica; Mendelson, Joseph R., III; Metcalf, Jessica L.; Meyer, Folker; Michelangeli, Fabian; Miller, Kim; Mills, David A.; Minich, Jeremiah; Mocali, Stefano; Moitinho-Silva, Lucas; Moore, Anni; Morgan-Kiss, Rachael M.; Munroe, Paul; Myrold, David; Neufeld, Josh D.; Ni, Yingying; Nicol, Graeme W.; Nielsen, Shaun; Nissimov, Jozef I.; Niu, Kefeng; Nolan, Matthew J.; Noyce, Karen; O'Brien, Sarah L.; Okamoto, Noriko; Orlando, Ludovic; Castellano, Yadira Ortiz; Osuolale, Olayinka; Oswald, Wyatt; Parnell, Jacob; Peralta-Sanchez, Juan M.; Petraitis, Peter; Pfister, Catherine; Pilon-Smits, Elizabeth; Piombino, Paola; Pointing, Stephen B.; Pollock, F. Joseph; Potter, Caitlin; Prithiviraj, Bharath; Quince, Christopher; Rani, Asha; Ranjan, Ravi; Rao, Subramanya; Rees, Andrew P.; Richardson, Miles; Riebesell, Ulf; Robinson, Carol; Rockne, Karl J.; Rodriguezl, Selena Marie; Rohwer, Forest; Roundstone, Wayne; Safran, Rebecca J.; Sangwan, Naseer; Sanz, Virginia; Schrenk, Matthew; Schrenzel, Mark D.; Scott, Nicole M.; Seger, Rita L.; Seguin-Orlando, Andaine; Seldin, Lucy; Seyler, Lauren M.; Shakhsheer, Baddr; Sheets, Gabriela M.; Shen, Congcong; Shi, Yu; Shin, Hakdong; Shogan, Benjamin D.; Shutler, Dave; Siegel, Jeffrey; Simmons, Steve; Sjoling, Sara; Smith, Daniel P.; Soler, Juan J.; Sperling, Martin; Steinberg, Peter D.; Stephens, Brent; Stevens, Melita A.; Taghavi, Safiyh; Tai, Vera; Tait, Karen; Tan, Chia L.; Tas, Neslihan; Taylor, D. Lee; Thomas, Torsten; Timling, Ina; Turner, Benjamin L.; Urich, Tim; Ursell, Luke K.; van der Lelie, Daniel; Van Treuren, William; van Zwieten, Lukas; Vargas-Robles, Daniela; Thurber, Rebecca Vega; Vitaglione, Paola; Walker, Donald A.; Walters, William A.; Wang, Shi; Wang, Tao; Weaver, Tom; Webster, Nicole S.; Wehrle, Beck; Weisenhorn, Pamela; Weiss, Sophie; Werner, Jeffrey J.; West, Kristin; Whitehead, Andrew; Whitehead, Susan R.; Whittingham, Linda A.; Willerslev, Eske; Williams, Allison E.; Wood, Stephen A.; Woodhams, Douglas C.; Yang, Yeqin; Zaneveld, Jesse; Zarraonaindia, Iratxe; Zhang, Qikun; Zhao, Hongxia (2017-11-23)
    Our growing awareness of the microbial world's importance and diversity contrasts starkly with our limited understanding of its fundamental structure. Despite recent advances in DNA sequencing, a lack of standardized protocols and common analytical frameworks impedes comparisons among studies, hindering the development of global inferences about microbial life on Earth. Here we present a meta-analysis of microbial community samples collected by hundreds of researchers for the Earth Microbiome Project. Coordinated protocols and new analytical methods, particularly the use of exact sequences instead of clustered operational taxonomic units, enable bacterial and archaeal ribosomal RNA gene sequences to be followed across multiple studies and allow us to explore patterns of diversity at an unprecedented scale. The result is both a reference database giving global context to DNA sequence data and a framework for incorporating data from future studies, fostering increasingly complete characterization of Earth's microbial diversity.
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    Using "Omics" and Integrated Multi-Omics Approaches to Guide Probiotic Selection to Mitigate Chytridiomycosis and Other Emerging Infectious Diseases
    Rebollar, Eria A.; Antwis, Rachael E.; Becker, Matthew H.; Belden, Lisa K.; Bletz, Molly C.; Brucker, Robert M.; Harrison, Xavier A.; Hughey, Myra C.; Kueneman, Jordan G.; Loudon, Andrew H.; McKenzie, Valerie; Medina, Daniel; Minbiole, Kevin P. C.; Rollins-Smith, Louise A.; Walke, Jenifer B.; Weiss, Sophie; Woodhams, Douglas C.; Harris, Reid N. (Frontiers, 2016-02-02)
    Emerging infectious diseases in wildlife are responsible for massive population declines. In amphibians, chytridiomycosis caused by Batrachochytrium dendrobatidis, Bd, has severely affected many amphibian populations and species around the world. One promising management strategy is probiotic bioaugmentation of antifungal bacteria on amphibian skin. In vivo experimental trials using bioaugmentation strategies have had mixed results, and therefore a more informed strategy is needed to select successful probiotic candidates. Metagenomic, transcriptomic, and metabolomic methods, colloquially called "omics," are approaches that can better inform probiotic selection and optimize selection protocols. The integration of multiple omic data using bioinformatic and statistical tools and in silico models that link bacterial community structure with bacterial defensive function can allow the identification of species involved in pathogen inhibition. We recommend using 16S rRNA gene amplicon sequencing and methods such as indicator species analysis, the Kolmogorov-Smirnov Measure, and co-occurrence networks to identify bacteria that are associated with pathogen resistance in field surveys and experimental trials. In addition to 16S amplicon sequencing, we recommend approaches that give insight into symbiont function such as shotgun metagenomics, metatranscriptomics, or metabolomics to maximize the probability of finding effective probiotic candidates, which can then be isolated in culture and tested in persistence and clinical trials. An effective mitigation strategy to ameliorate chytridiomycosis and other emerging infectious diseases is necessary; the advancement of omic methods and the integration of multiple omic data provide a promising avenue toward conservation of imperiled species.