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Browsing by Author "Singh, Garhi"

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    MetaStorm: A Public Resource for Customizable Metagenomics Annotation
    Arango-Argoty, Gustavo; Singh, Garhi; Heath, Lenwood S.; Pruden, Amy; Xiao, Weidong; Zhang, Liqing (PLOS, 2016-09-15)
    Metagenomics is a trending research area, calling for the need to analyze large quantities of data generated from next generation DNA sequencing technologies. The need to store, retrieve, analyze, share, and visualize such data challenges current online computational systems. Interpretationand annotation of specific information is especially a challenge for metagenomic data sets derived from environmental samples, because current annotation systems only offer broad classification of microbial diversity and function. Moreover, existing resources are not configured to readily address common questions relevant to environmental systems. Here we developed a new online user-friendly metagenomic analysis server called MetaStorm (http://bench.cs.vt.edu/MetaStorm/), which facilitates customization of computational analysis for metagenomic data sets. Users can upload their own reference databases to tailor the metagenomics annotation to focus on various taxonomic and functional gene markers of interest. MetaStormoffers two major analysis pipelines: an assembly-based annotation pipeline and the standard read annotation pipeline used by existing web servers. These pipelines can be selected individually or together. Overall, MetaStorm provides enhanced interactive visualization to allow researchers to explore and manipulate taxonomy and functional annotation at various levels of resolution.
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    Solid-like dynamics in ultrathin films of polymeric liquids
    Singh, Garhi; Saraf, Ravi F.; Martin, Y. (AIP Publishing, 2003-12-01)
    In this letter, we demonstrate that, at mesoscales, nonferroelectric liquid films of poly(dimethyl siloxane) exhibit significant electrostriction not present in the corresponding bulk state. Remarkably, the observed electrostrictive effect has a response time <20 mus in contrast to >5 ms recorded in conventional bulk (ferroelectric) polymers. The emergence of this fast electrostrictive strain in thin films is explained in terms of the amalgamation of two contrasting dynamic features-the influence of a highly mobile, viscous layer (at the air/film interface) on the less-mobile, but fast responding, solid-like layer at the film/substrate interface. The effect is observed for thickness below 200 nm. (C) 2003 American Institute of Physics.