Browsing by Author "Tidwell, R. R."
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- Prevalence of antibodies to Leishmania infantum and Trypanosoma cruzi in wild canids from South CarolinaRosypal, A. C.; Tidwell, R. R.; Lindsay, David S. (American Society of Parasitology, 2007-08)Wild canids are reservoir hosts for Leishmania infantum and Trypanosoma cruzi.. The present study examined the prevalence of antibodies to these zoonotic parasites in a population of wild canids from a nonagricultural setting in South Carolina. Sera from 26 gray foxes (Urocyon cinereoargenteus) and 2 coyotes (Canis latrans) were examined for antibodies to L. infantum and T. cruzi using the indirect immunofluorescent antibody test and commercially available parasite-specific immunochromatigraphic strip assays. Antibodies to L. infantinn were not detected by either assay in gray foxes or coyotes. Two (8%) of 26 gray foxes were positive in both the T. cruzi immunofluorescent antibody and strip assays. Antibodies to T. cruzi were not detected in coyotes. Results from this study indicate that wild canids are exposed to T. cruzi, but not L. infantum. in this geographic region.
- Surveillance for Antibodies to Leishmania spp. in Dogs From Sri LankaRosypal, A. C.; Tripp, S.; Kinlaw, C.; Hailemariam, S.; Tidwell, R. R.; Lindsay, David S.; Rajapakse, Rpvj; Sreekumar, C.; Dubey, Jitender P. (American Society of Parasitology, 2010-02)The global distribution of leishmaniasis is rapidly expanding into new geographic regions. Dogs are the primary reservoir hosts for human visceral leishmaniasis caused by infection with Leishmania infantum. Natural infections with other Leishmania spp. can occur in dogs, but their role as reservoir hosts for other species of Leishmania is uncertain. Leishmania donovani is traditionally considered a visceralizing anthroponotic species; however, cutaneous leishmaniasis caused by L. donovani has been reported 111 Sri Lanka. In the present study, sera from 114 dogs in Sri Lanka were examined for antibodies to visceralizing Leishmania spp. Sera were tested by the canine immunochromatographic strip assays based on recombinant K39 antigen. Anti-Leishmania spp. antibodies were detectable in 1 of 114 (0.9%) dogs from Sri Lanka. Nonetheless, serological evidence suggests that leishmaniasis may be an emerging zoonosis in Sri Lanka.
- Survey of Dogs From Vietnam for Antibodies to Visceralizing Leishmania sppRosypal, A. C.; Hailemariam, S.; Wekheye, V.; Huong, L. T. T.; Dubey, Jitender P.; Lindsay, David S.; Tidwell, R. R. (American Society of Parasitology, 2009-06)Cases of visceral leishmaniasis, one of the most neglected tropical diseases, are increasing globally. Dogs are considered all important reservoir host for visceral leishmaniasis in people. The first cases of human visceral leishmaniasis in Vietnam have recently been reported. Blood samples were collected from 41 dogs in rural Vietnam. Sera were examined for antibodies to visceralizing Leishmania spp. by canine immunochromatographic strip assays based on recombinant K39 antigen. Antibodies to Leishmania spp. were not detected in ally of the dogs tested. Results from this study suggest that rural dogs are not likely to be involved in the emergence of human visceral leishmaniasis in Vietnam.