Browsing by Author "Walker, D. H."

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  • Integrating research results into decision making about natural resource management at a catchment scale
    Walker, D. H.; Cowell, S. G.; Johnson, A. K. L. (Elsevier Science, 2001)
    The operational reality behind the rhetoric of integrated natural resource management poses significant challenges for resource managers, resource use planners and researchers. A variety of frameworks for integrated resource planning and use have been espoused. These tend to reflect the bias of the discipline or stakeholder group fostering the approach and may therefore be unpalatable to, and ignored by, other groups. In this paper, we are concerned with improving the integration of research outcomes into decision making. Rather than propose a framework, we take a pragmatic view of the roles of managers, planners and scientists. In doing so, we draw principally on practical experience derived from an initiative in a rural catchment in tropical Australia. On this basis, we propose a particular and emerging role in designing approaches to adaptive decision support that provide opportunities for integrating research outcomes into decision making. -Elsevier/Author's abstract
  • A systems approach to the evaluation of natural resource management initiatives
    Bellamy, J. A.; Walker, D. H.; McDonald, G. T.; Syme, G. J. (Academic Press, 2001)
    The data presented pertain to a research article titled “Heme Oxygenase 1 Up-Regulates Glomerular Decay Accelerating Factor Expression and Minimizes Complement Deposition and Injury” (Detsika et al., 2016). The present work provides additional data on induction and immunolocalization of heme oxygenase (HO)-1 (an antioxidant enzyme) and decay-accelerating factor (DAF) (a complement activation inhibitor) in isolated rat glomeruli and in glomerular epithelial cells (podocytes) in response to Iron Protoporphyrin IX (FePP, heme), and to non-iron protoporphyrins (PPs) with varying metal functionalities (ZnPP, SnPP), including a metal-devoid PP. Induction and immuno-localization of HO-1 and DAF in response to these metalloporphyrins (MP) were assessed using western blot analyses and confocal microscopy in isolated glomeruli and in cultured podocytes. These analyses identified podocytes as a major localization site of HO-1 and DAF induction in response to the aforementioned MPs. Effects of these MPs on a key glomerular structural protein, Nephrin, are also reported. The data identify MPs most and least capable of inducing DAF and reducing Nephrin expression and provide clues into expected outcomes of animal studies assessing MP efficacy in upregulating the cytoprotective proteins HO-1 and DAF.