Browsing by Author "Wang, Ying"
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- AI-Powered Real-Time Channel Awareness and 5G NR Radio Access Network Scheduling OptimizationWang, Ying; Gorski, Adam; DaSilva, Luiz A. (IEEE, 2021-04-19)As with any other wireless technology, 5G is not immune to jamming. To achieve consistent performance, network resource scheduling must be optimized in a way that reacts to jamming in the NR channel environment. This paper presents a cognitive system for real-time Channel Awareness and Radio Access Network (RAN) Scheduling (CARS) optimization based on multi-dimensional temporal machine learning models. Our system automatically detects and classifies jamming in the channel environment and optimizes scheduling based on classification results and collected link parameters. Based on over-the-air (OTA) experiments, detection and classification time is less than 0.8 seconds, which enables real-time optimization. The system is evaluated and verified for OTA experimentation through integration to our end-to-end NR system. An Automated Jamming Module (AJM) is designed and implemented. Connecting the AJM to our NR system enables a comprehensive evaluation environment for our Jamming Detection and Classification Model (JDCM) and Modulation and Coding Scheme optimization model. The improvement in connection resiliency against Control Resource Set jamming is proof of the CARS concept for real-time channel awareness and scheduling optimization. Depending on channel conditions, CARS achieves a 30% or higher improvement in NR system throughput.
- Development and Characterization of Advanced Polymer Electrolyte for Energy Storage and Conversion DevicesWang, Ying (Virginia Tech, 2017-01-09)Among the myraid energy storage technologies, polymer electrolytes have been widely employed in diverse applications such as fuel cell membranes, battery separators, mechanical actuators, reverse-osmosis membranes and solar cells. The polymer electrolytes used for these applications usually require a combination of properties, including anisotropic orientation, tunable modulus, high ionic conductivity, light weight, high thermal stability and low cost. These critical properties have motivated researchers to find next-generation polymer electrolytes, for example ion gels. This dissertation aims to develop and characterize a new class of ion gel electrolytes based on ionic liquids and a rigid-rod polyelectrolyte. The rigid-rod polyelectrolyte poly (2,2'-disulfonyl-4,4'-benzidine terephthalamide) (PBDT) is a water-miscible system and forms a liquid crystal phase above a critical concentration. The diverse properties and broad applications of this rigid-rod polyelectrolyte may originate from the double helical conformation of PBDT molecular chains. We primarily develop an ionic liquid-based polymer gel electrolyte that possesses the following exceptional combination of properties: transport anisotropy up to 3.5×, high ionic conductivity (up to 8 mS cm⁻¹), widely tunable modulus (0.03 – 3 GPa) and high thermal stability (up to 300°C). This unique platform that combines ionic liquid and polyelectrolyte is essential to develop more advanced materials for broader applications. After we obtain the ion gels, we then mainly focus on modifying and then applying them in Li-metal batteries. As a next generation of Li batteries, the Li-metal battery offers higher energy capacity compared to the current Li-ion battery, thus satisfying our requirements in developing longer-lasting batteries for portable devices and even electric vehicles. However, Li dendrite growth on the Li metal anode has limited the pratical application of Li-metal batteries. This unexpected Li dendrite growth can be suppressed by developing polymer separators with high modulus (~ Gpa), while maintaining enough ionic conductivity (~ 1 mS/cm). Here, we describe an advanced solid-state electrolyte based on a sulfonated aramid rigid-rod polymer, an ionic liquid (IL), and a lithium salt, showing promise to make a breakthrough. This unique fabrication platform can be a milestone in discovering next-generation electrolyte materials.
- Double helical conformation and extreme rigidity in a rodlike polyelectrolyteWang, Ying; He, Yadong; Yu, Zhou; Gao, Jianwei; ten Brinck, Stephanie; Slebodnick, Carla; Fahs, Gregory B.; Zanelotti, Curt J.; Hegde, Maruti; Moore, Robert Bowen; Ensing, Bernd; Dingemans, Theo J.; Qiao, Rui; Madsen, Louis A. (Nature Publishing Group, 2019-02-18)The ubiquitous biomacromolecule DNA has an axial rigidity persistence length of ~50 nm, driven by its elegant double helical structure. While double and multiple helix structures appear widely in nature, only rarely are these found in synthetic non-chiral macromolecules. Here we report a double helical conformation in the densely charged aromatic polyamide poly(2,2′-disulfonyl-4,4′-benzidine terephthalamide) or PBDT. This double helix macromolecule represents one of the most rigid simple molecular structures known, exhibiting an extremely high axial persistence length (~1 micrometer). We present X-ray diffraction, NMR spectroscopy, and molecular dynamics (MD) simulations that reveal and confirm the double helical conformation. The discovery of this extreme rigidity in combination with high charge density gives insight into the self-assembly of molecular ionic composites with high mechanical modulus (~ 1 GPa) yet with liquid-like ion motions inside, and provides fodder for formation of other 1D-reinforced composites. © 2019, The Author(s).
- Dynamic Cellular Cognitive SystemWang, Ying (Virginia Tech, 2009-09-25)Dynamic Cellular Cognitive System (DCCS) serves as a cognitive network for white space devices in TV white space. It is also designed to provide quality communications for first responders in area with damaged wireless communication infrastructure. In DCCS network, diverse types of communication devices interoperate, communicate, and cooperate with high spectrum efficiency in a Dynamic Spectrum Access (DSA) scenario. DCCS can expand to a broad geographical distribution via linking to existing infrastructure. DCCS can quickly form a network to accommodate a diverse set of devices in natural disaster areas. It can also recover the infrastructure in a blind spot, for example, a subway or mountain area. Its portability and low cost make it feasible for commercial applications. This dissertation starts with an overview of DCCS network. DCCS defines a cognitive radio network and a set of protocols that each cognitive radio node inside the network must adopt to function as a user within the group. Multiple secondary users cooperate based on a fair and efficient scheme without losing the flexibility and self adaptation features. The basic unit of DCCS is a cell. A set of protocols and algorithms are defined to meet the communication requirement for intra-cell communications. DCCS includes multiple layers and multiple protocols. This dissertation gives a comprehensive description and analysis of building a DCCS network. It covers the network architecture, physical and Medium Access Control (MAC) layers for data and command transmission, spectrum management in DSA scenario, signal classification and synchronization and describes a working prototype of DCCS. Two key technologies of intra-cell communication are spectrum management and Universal Classification and Synchronization (UCS). A channel allocation algorithm based on calculating the throughput of an available is designed and the performance is analyzed. UCS is conceived as a self-contained system which can detect, classify, and synchronize with a received signal and extract all parameters needed for physical layer demodulation. It enables the accommodation of non-cognitive devices and improves communication quality by allowing a cognitive receiver to track physical layer changes at the transmitter. Inter-cell communications are the backhaul connections of DCCS. This dissertation discusses two approaches to obtaining spectrum for inter-cell communications. A temporary leasing approach focuses on the policy aspects, and the other approach is based on using OFDMA to combine separate narrowband channels into a wideband channel that can meet the inter-cell communications throughput requirements. A prototype of DCCS implemented on GNU radio and USRP platform is included in the dissertation. It serves as the proof of concept of DCCS.
- Dynamic cellular cognitive system(United States Patent and Trademark Office, 2012-01-10)High quality communications among a diverse set of cognitive radio (CR) nodes is permitted while minimizing interference to primary and other secondary users by employing Dynamic Spectrum Access (DSA) in a Dynamic Cellular Cognitive System (DCCS). Diverse device types interoperate, cooperate, and communicate with high spectrum efficiency and do not require infrastructure to form the network. The dynamic cellular cognitive system can expand to a wider geographical distribution via linking to existing infrastructure.
- Fuzz Testing Architecture Used for Vulnerability Detection in Wireless SystemsMayhew, Stephen Richard (Virginia Tech, 2022-06-23)The wireless world of today is essential to the everyday life of millions of people. Wireless technology is evolving at a rapid pace that's speed outmatches what the previous testing can handle. This necessitates the need for smarter and faster testing methods. One of the recent fast and efficient testing methods is fuzz testing. Fuzz testing is the generation and injection of unexpected input called "fuzzed" input for a system by slightly changing a base input hundreds or even thousands of times and introducing each change into a system to observe its effects. In this thesis, we developed and implemented a fuzz testing architecture to test 5G wireless system vulnerabilities. The proposed design uses multiple open-source software to create a virtual wireless environment for testing the fuzzed inputs' effects on the wireless attach procedure. Having an accessible and adaptable fuzzing architecture to use with wireless networks will help against malicious parties. Due to 5G simulation technology still being developed and the cost of ready-made 5G testing equipment, the architecture was implemented in an LTE environment using the srsRAN LTE simulation software, the Boofuzz fuzzing software, and Wireshark packet capture software. The results show consistent effects of the fuzz testing on the outputs of the LTE eNB. We also include a discussion of our future suggestions to improve the proposed fuzzing architecture.
- Growth Hormone and Nutritional Regulation of Insulin-Like Growth Factor-I Gene ExpressionWang, Ying (Virginia Tech, 2005-12-08)The objectives of this research were to characterize insulin-like growth factor-I (IGF-I) gene expression in cattle, to determine how IGF-I gene expression is affected by nutritional intake and growth hormone (GH) in cattle, and to identify the regulatory DNA region that mediates GH stimulation of IGF-I gene expression. It was found that transcription of the IGF-I gene in cattle was initiated from both exon 1 and exon 2, generating class 1 and class 2 IGF-I mRNA, respectively. Both classes of IGF-I mRNA appeared to be ubiquitously expressed, with the highest level in liver and with class 1 being more abundant than class 2 in all tissues examined. Class 1 IGF-I mRNA may be also translated more efficiently than class 2 IGF-I mRNA. Liver expression of IGF-I mRNA was decreased (P < 0.01) by food deprivation in cattle, and this decrease was due to an equivalent decrease in both classes of IGF-I mRNA. Liver expression of IGF-I mRNA was increased (P < 0.01) by GH, and this increase resulted mainly from increased expression of class 2 IGF-I mRNA. Using cotransfection analyses, a ~700 bp chromosomal region ~75 kb 5' from the first exon of the human IGF-I gene was found to enhance reporter gene expression in the presence of constitutively active signal transducer and activator of transcription 5 (STAT5) proteins, transcription factors that are known to be essential for GH-increased IGF-I gene expression. This 700 bp DNA region contains two STAT5-binding sites that appear to be conserved in mammals including cattle. Electrophoretic mobility shift assays and cotransfection analyses confirmed their ability to bind to STAT5 proteins and to mediate STAT5 activation of gene expression, respectively. Chromatin immunoprecipitation assays indicated that overexpressed constitutively active STAT5b protein bound to the chromosomal region containing these two STAT5-binding sites in Hep G2 cells, and this binding was associated with increased expression of IGF-I mRNA. These two STAT5-binding sites were also able to mediate GH-induced STAT5 activation of gene expression in reconstituted GH-responsive cells. These results together suggest that the distal DNA region that contains two STAT5-binding sites may mediate GH-induced STAT5 activation of IGF-I gene transcription in vivo.
- Growth hormone stimulates hepatic expression of bovine growth hormone receptor messenger ribonucleic acid through signal transducer and activator of transcription 5 activation of a major growth hormone receptor gene promoterJiang, Honglin; Wang, Ying; Wu, Miaozong; Gu, Zhiliang; Frank, Stuart J.; Torres-Diaz, Roberto (Endocrine Society, 2007-07)The objective of this study was to determine whether and how GH regulates hepatic expression of GH receptor (GHR) mRNA in cattle. Ribonuclease protection assays revealed that injection of GH in a slow-release formula increased both hepatic GHR and IGF-I mRNAs 1 wk after the injection. The increases in GHR and IGF-I mRNAs were highly correlated. Western blot analysis showed that the injection also increased liver GHR protein level. In cattle and other mammals, hepatic GHR mRNA is expressed as variants that differ in the 5'-untranslated region due to the use of different promoters in transcription and/or alternative splicing. We found that GH increased the expression of the liver-specific GHR mRNA variant GHR1A without affecting the other two major GHR mRNA variants in the bovine liver, GHR1B and GHR1C. In transient transfection analyses, GH could robustly activate reporter gene expression from a 2.7-kb GHR1A promoter, suggesting that GH augmentation of GHR1A mRNA expression in the liver is at least partially mediated at the transcriptional level. Additional transfection analyses of serially 5'-truncated fragments of this promoter narrowed the GH-responsive sequence element down to a 210-bp region that contained a putative signal transducer and activator of transcription 5 (STAT5) binding site. EMSAs demonstrated that this putative STAT5 binding site was able to bind to STAT5b protein. In cotransfection assays, deletion of this putative STAT5 binding site abolished most of the GH response of the GHR1A promoter. Like 1-wk GH action, 6-h (i.e. short-term) GH action also increased liver expression of GHR1A and total GHR mRNAs in cattle. These observations together suggest that GH directly stimulates the expression of one GHR mRNA variant, GHR1A, through binding STAT5 to its promoter, thereby increasing GHR mRNA and protein expression in the bovine liver.
- Growth Hormone-Activated STAT5 May Indirectly Stimulate IGF-I Gene Transcription through HNF-3 gammaEleswarapu, Satyanarayana; Ge, Xiaomei; Wang, Ying; Yu, Jie; Jiang, Honglin (Endocrine Society, 2009-12)IGF-I is abundantly expressed in the liver under the stimulation of GH. We showed previously that expression of hepatocyte nuclear factor (HNF)-3 gamma, a liver-enriched transcription factor, was strongly stimulated by GH in bovine liver. In this study, we determined whether GH-increased HNF-3 gamma might contribute to GH stimulation of IGF-I gene expression in bovine liver and the underlying mechanism. A sequence analysis of the bovine IGF-I promoter revealed three putative HNF-3 binding sites, which all appear to be conserved in mammals. Chromatin immunoprecipitation assays showed that GH injection increased binding of HNF-3 gamma to the IGF-I promoter in bovine liver. Gel-shift assays indicated that one of the three putative HNF-3 binding sites, HNF-3 binding site 1, bound to the HNF-3 gamma protein from bovine liver with high affinity. Cotransfection analyses demonstrated that this HNF-3 binding site was essential for the transcriptional response of the IGF-I promoter to HNF-3 gamma in CHO cells and to GH in primary mouse hepatocytes. Using similar approaches, we found that GH increased binding of the signal transducer and activator of transcription 5 (STAT5) to the HNF-3 gamma promoter in bovine liver, that this binding occurred at a conserved STAT5 binding site, and that this STAT5 binding site was necessary for the HNF-3 gamma promoter to respond to GH. Taken together, these results suggest that in addition to direct action, GH-activated STAT5 may also indirectly stimulate IGF-I gene transcription in the liver by directly enhancing the expression of the HNF-3 gamma gene. (Molecular Endocrinology 23: 2026-2037, 2009)