Browsing by Author "Zhao, Jianxin"
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- Making Digital Libraries Flexible, Scalable and Reliable: Reengineering the MARIAN System in JAVAZhao, Jianxin (Virginia Tech, 1999-06-22)There is a great need for digital libraries that are flexible, scalable, and reliable. Few such systems exist. Little is known about how to build them. This thesis addresses these problems by enhancing a prototype digital library system with the aim of making it more flexible, scalable, and reliable. We hypothesize that: 1) adding a new (user information) layer and maintaining weak coupling in the design of a digital library system can help achieve system flexibility; 2) optimizing network connection usage and facilitating distribution of computation and disk operations in system design can help achieve system scalability; and 3) applying good software processes can help university students produce a very reliable system. Approaches based on the above hypothesis were used in the project of Reengineering the MARIAN System in Java. The results of the project and experiments verified the correctness of the hypothesis. The results of this thesis may help inform future digital library design and implementation projects to produce flexible, scalable, and reliable systems.
- Quantitative Genetic Background of the Host Influences Gut Microbiomes in ChickensZhao, Lele; Wang, Gang; Siegel, Paul B.; He, Chuan; Wang, Hezhong; Zhao, Wenjing; Zhai, Zhengxiao; Tian, Fengwei; Zhao, Jianxin; Zhang, Hao; Sun, Zikui; Chen, Wei; Zhang, Yan; Meng, He (Nature Publishing Group, 2013-01)Host genotype and gender are among the factors that influence the composition of gut microbiota. We studied the population structure of gut microbiota in two lines of chickens maintained under the same husbandry and dietary regimes. The lines, which originated from a common founder population, had undergone 54 generations of selection for high (HW) or low (LW) 56-day body weight, and now differ by more than 10-fold in body weight at selection age. Of 190 microbiome species, 68 were affected by genotype (line), gender, and genotype by gender interactions. Fifteen of the 68 species belong to Lactobacillus. Species affected by genotype, gender, and the genotype by gender interaction, were 29, 48, and 12, respectively. Species affected by gender were 30 and 17 in the HW and LW lines, respectively. Thus, under a common diet and husbandry host quantitative genotype and gender influenced gut microbiota composite.
- Use and Usability in a Digital Library Search SystemFrance, Robert K.; Nowell, Lucy Terry; Fox, Edward A.; Saad, Rani A.; Zhao, Jianxin (Virginia Tech Digital Library Research Laboratory, 1999)Digital libraries must reach out to users from all walks of life, serving information needs at all levels. To do this, they must attain high standards of usability over an extremely broad audience. This paper details the evolution of one important digital library component as it has grown in functionality and usefulness over several years of use by a live, unrestricted community. Central to its evolution have been user studies, analysis of use patterns, and formative usability evaluation. We extrapolate that all three components are necessary in the production of successful digital library systems.