Now showing items 1-4 of 4
A Computational Framework for Assessing and Optimizing the Performance of Observational Networks in 4D-Var Data Assimilation
(Virginia Tech, 2013-09-04)
A deep scientific understanding of complex physical systems, such as the atmosphere, can be achieved neither by direct measurements nor by numerical simulations alone. Data assimilation is a rigorous procedure to fuse ...
Fréchet Sensitivity Analysis and Parameter Estimation in Groundwater Flow Models
(Virginia Tech, 2013-05-09)
In this work we develop and analyze algorithms motivated by the parameter estimation problem corresponding to a multilayer aquifer/interbed groundwater flow model. The parameter estimation problem is formulated as an ...
Computational and Experimental Modeling of the Bioheat Transfer Process of Perfusion in Tissue Applied to Burn Wounds
(Virginia Tech, 2013-04-29)
A new mathematical model has been developed along with a new parameter estimation routine using surface temperature and heat flux measurements to estimate blood perfusion and thermal resistance in living tissue. Dynamic ...
Estimation of gene network parameters from imaging cytometry data
(Virginia Tech, 2013-05-23)
Synthetic biology endeavors to forward engineer genetic circuits with novel function. A major inspiration for the field has been the enormous success in the engineering of digital electronic circuits over the past half ...