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Identifying and forecasting importation and asymptomatic spreaders of multi-drug resistant organisms in hospital settings
Cui, Jiaming; Heavey, Jack; Klein, Eili; Madden, Gregory R.; Sifri, Costi D.; Vullikanti, Anil; Prakash, B. Aditya (Nature Portfolio, 2025-03-07)
Healthcare-associated infections (HAIs) from multi-drug resistant organisms (MDROs) pose a significant challenge for healthcare systems. Patients can arrive at hospitals already infected ("importation”) or acquire infections during their stay ("nosocomial infection”). Many cases, often asymptomatic, complicate rapid identification due to testing limitations and delays. Although recent advancements in mathematical modeling and machine learning have aimed to identify at-risk patients, these methods face challenges: transmission models often overlook valuable electronic health record (EHR) data, while machine learning approaches typically lack mechanistic insights into underlying processes. To address these issues, we propose NeurABM, a novel framework that integrates neural networks and agent-based models (ABM) to leverage the strengths of both methods. NeurABM simultaneously learns a neural network for patient-level importation predictions and an ABM for infection identification. Our findings show that NeurABM significantly outperforms existing methods, marking a breakthrough in accurately identifying importation cases and forecasting future nosocomial infections in clinical practice.
Performance of a Modular Ton-Scale Pixel-Readout Liquid Argon Time Projection Chamber
Abud, A. Abed; Abi, B.; Acciarri, R.; Acero, M. A.; Adames, M. R.; Adamov, G.; Adamowski, M.; Adams, D.; Adinolfi, M.; Adriano, C.; Aduszkiewicz, A.; Aguilar, J.; Aimard, B.; Akbar, F.; Allison, K.; Monsalve, S. Alonso; Alrashed, M.; Alton, A.; Alvarez, R.; Alves, T.; Amar, H.; Amedo, P.; Anderson, J.; Andrade, D. A.; Andreopoulos, C.; Andreotti, M.; Andrews, M. P.; Andrianala, F.; Andringa, S.; Anfimov, N.; Ankowski, A.; Antoniassi, M.; Antonova, M.; Antoshkin, A.; Aranda-Fernandez, A.; Arellano, L.; Arrieta Diaz, E.; Arroyave, M. A.; Asaadi, J.; Ashkenazi, A.; Asner, D.; Asquith, L.; Atkin, E.; Auguste, D.; Aurisano, A.; Aushev, V.; Autiero, D.; Azfar, F.; Back, A.; Back, H.; Back, J. J.; Bagaturia, I.; Bagby, L.; Balashov, N.; Balasubramanian, S.; Baldi, P.; Baldini, W.; Baldonedo, J.; Baller, B.; Bambah, B.; Banerjee, R.; Barao, F.; Barenboim, G.; Alzas, PB Arham B. A.; Barker, G. J.; Barkhouse, W.; Barr, G.; Barranco Monarca, J.; Barros, A.; Barros, N.; Barrow, D.; Barrow, J. L.; Basharina-Freshville, A.; Bashyal, A.; Basque, V.; Batchelor, C.; Bathe-Peters, L.; Battat, J. B. R.; Battisti, F.; Bay, F.; Bazetto, M. C. Q.; Bazo Alba, J. L. L.; Beacom, J. F.; Bechetoille, E.; Behera, B.; Belchior, E.; Bell, G.; Bellantoni, L.; Bellettini, G.; Bellini, V.; Beltramello, O.; Benekos, N.; Benitez Montiel, C.; Benjamin, D.; Bento Neves, F.; Berger, J.; Berkman, S.; Bernal, J.; Bernardini, P.; Bersani, A.; Bertolucci, S.; Betancourt, M.; Betancur Rodriguez, A.; Bevan, A.; Bezawada, Y.; Bezerra, A. T.; Bezerra, T. J.; Bhat, A.; Bhatnagar, V.; Bhatt, J.; Bhattacharjee, M.; Bhattacharya, M.; Bhuller, S.; Bhuyan, B.; Biagi, S.; Bian, J.; Biery, K.; Bilki, B.; Bishai, M.; Bitadze, A.; Blake, A.; Blaszczyk, F. D.; Blazey, G. C.; Blucher, E.; Bogenschuetz, J.; Boissevain, J.; Bolognesi, S.; Bolton, T.; Bomben, L.; Bonesini, M.; Bonilla-Diaz, C.; Bonini, F.; Booth, A.; Boran, F.; Bordoni, S.; Borges Merlo, R.; Borkum, A.; Bostan, N.; Bracinik, J.; Braga, D.; Brahma, B.; Brailsford, D.; Bramati, F.; Branca, A.; Brandt, A.; Bremer, J.; Brew, C.; Brice, S. J.; Brio, V.; Brizzolari, C.; Bromberg, C.; Brooke, J.; Bross, A.; Brunetti, G.; Brunetti, M.; Buchanan, N.; Budd, H.; Buergi, J.; Burgardt, D.; Butchart, S.; Caceres, G.; Cagnoli, I.; Cai, T.; Calabrese, R.; Calcutt, J.; Calin, M.; Calivers, L.; Calvo, E.; Caminata, A.; Camino, A. F.; Campanelli, W.; Campani, A.; Benitez, A. Campos; Canci, N.; Capo, J.; Caracas, I.; Caratelli, D.; Carber, D.; Carceller, J. M.; Carini, G.; Carlus, B.; Carneiro, M. F.; Carniti, P.; Terrazas, I. Caro; Carranza, H.; Carrara, N.; Carroll, L.; Carroll, T.; Carter, A.; Casarejos, E.; Casazza, D.; Castano Forero, J. F.; Castano, F. 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F.; Stepanova, A.; Stewart, J.; Stillwell, B.; Stock, J.; Stocker, F.; Stokes, T.; Strait, M.; Strauss, T.; Strigari, L.; Stuart, A.; Suarez, J. G.; Subash, J.; Surdo, A.; Suter, L.; Sutera, C. M.; Sutton, K.; Suvorov, Y.; Svoboda, R.; Swain, S. K.; Szczerbinska, B.; Szelc, A. M.; Sztuc, A.; Taffara, A.; Talukdar, N.; Tamara, J.; Tanaka, H. A.; Tang, S.; Taniuchi, N.; Tapia Casanova, A. M.; Oregui, B. Tapia; Tapper, A.; Tariq, S.; Tarpara, E.; Tatar, E.; Tayloe, R.; Tedeschi, D.; Teklu, A. M.; Vidal, J. Tena; Tennessen, P.; Tenti, M.; Terao, K.; Terranova, F.; Testera, G.; Thakore, T.; Thea, A.; Thiebault, A.; Thomas, S.; Thompson, A.; Thorn, C.; Timm, S. C.; Tiras, E.; Tishchenko, V.; Todorovic, N.; Tomassetti, L.; Tonazzo, A.; Torbunov, D.; Torti, M.; Tortola, M.; Tortorici, F.; Tosi, N.; Totani, D.; Toups, M.; Touramanis, C.; Tran, D.; Travaglini, R.; Trevor, J.; Triller, E.; Trilov, S.; Truchon, J.; Truncali, D.; Trzaska, W. H.; Tsai, Y.; Tsai, Y. -T.; Tsamalaidze, Z.; Tsang, K. V.; Tsverava, N.; Tu, S. Z.; Tufanli, S.; Tunnell, C.; Turner, J.; Tuzi, M.; Tyler, J.; Tyley, E.; Tzanov, M.; Uchida, M. A.; Urena Gonzalez, J.; Urheim, J.; Usher, T.; Utaegbulam, H.; Uzunyan, S.; Vagins, M. R.; Vahle, P.; Valder, S.; Valdiviesso, G. A.; Valencia, E.; Valentim, R.; Vallari, Z.; Vallazza, E.; Valle, J. W. F.; Van Berg, R.; Van de Water, R. G.; Forero, D. V.; Vannozzi, A.; Van Nuland-Troost, M.; Varanini, F.; Oliva, D. Vargas; Vasina, S.; Vaughan, N.; Vaziri, K.; Vazquez-Ramos, A.; Vega, J.; Ventura, S.; Verdugo, A.; Vergani, S.; Verzocchi, M.; Vetter, K.; Vicenzi, M.; Vieira De Souza, H.; Vignoli, C.; Vilela, C.; Villa, E.; Viola, S.; Viren, B.; Vizcaya-Hernandez, A.; Vrba, T.; Vuong, Q.; Waldron, A. V.; Wallbank, M.; Walsh, J.; Walton, T.; Wang, H.; Wang, J.; Wang, L.; Wang, M. H. L. S.; Wang, X.; Wang, Y.; Warburton, K.; Warner, D.; Warsame, L.; Wascko, M. O.; Waters, D.; Watson, A.; Wawrowska, K.; Weber, A.; Weber, C. M.; Weber, M.; Wei, H.; Weinstein, A.; Wenzel, H.; Westerdale, S.; Wetstein, M.; Whalen, K.; Whilhelmi, J.; White, A.; Whitehead, L. H.; Whittington, D.; Wilking, M. J.; Wilkinson, A.; Wilkinson, C.; Wilson, F.; Wilson, R. J.; Winter, P.; Wisniewski, W.; Wolcott, J.; Wolfs, J.; Wongjirad, T.; Wood, A.; Wood, K.; Worcester, E.; Worcester, M.; Wospakrik, M.; Wresilo, K.; Wret, C.; Wu, S.; Wu, W.; Wurm, M.; Wyenberg, J.; Xiao, Y.; Xiotidis, I.; Yaeggy, B.; Yahlali, N.; Yandel, E.; Yang, K.; Yang, T.; Yankelevich, A.; Yershov, N.; Yonehara, K.; Young, T.; Yu, B.; Yu, H.; Yu, J.; Yu, Y.; Yuan, W.; Zaki, R.; Zalesak, J.; Zambelli, L.; Zamorano, B.; Zani, A.; Zapata, O.; Zazueta, L.; Zeller, G. P.; Zennamo, J.; Zeug, K.; Zhang, C.; Zhang, S.; Zhao, M.; Zhivun, E.; Zimmerman, E. D.; Zucchelli, S.; Zuklin, J.; Zutshi, V.; Zwaska, R. (MDPI, 2025-09-11)
The Module-0 Demonstrator is a single-phase 600 kg liquid argon time projection chamber operated as a prototype for the DUNE liquid argon near detector. Based on the ArgonCube design concept, Module-0 features a novel 80k-channel pixelated charge readout and advanced high-coverage photon detection system. In this paper, we present an analysis of an eight-day data set consisting of 25 million cosmic ray events collected in the spring of 2021. We use this sample to demonstrate the imaging performance of the charge and light readout systems as well as the signal correlations between the two. We also report argon purity and detector uniformity measurements and provide comparisons to detector simulations.
Historias for the Empire: Indigenous Translators and the Reproductions of Linguistic Conquest
Caraccioli, Mauro J. (University of Michigan Press, 2026-02)
Principles for better environmental education field trips for early adolescent youth in the United States: an empirical study
Stern, Marc J.; Powell, Robert B.; Frensley, B. Troy; Anderson, Kelley C.; Kiewra, Lydia; Pownall, Malia; Schmitt, Talia; Thorpe, Emily G. (Routledge, 2025-05-12)
Which approaches lead to better outcomes for participants in environmental education (EE) field trips? This manuscript builds upon previous large-sample quantitative research that identified effective elements of single-day EE field trip programs for early adolescent youth across the USA. In this mixed-methods study, we observed 87 EE-focused school field trips in the USA and then surveyed youth participants immediately afterwards. We used the student surveys to quantitatively distinguish the top-performing quartile of programs from the bottom quartile. We then examined in-depth qualitative fieldnotes on each program in the top and bottom quartiles. Our analyses revealed six key principles that distinguished the programs with the most positive student outcomes from those with the least positive: (1) ensuring basic needs (physiological and safety) are met; (2) ensuring instructional clarity; (3) providing emotional support for students; (4) highlighting the novelty of the activities and setting; (5) maintaining or restoring student attention; and (6) providing a cohesive and thematic experience with clear purpose. There are many ways to embody the six principles. We share examples for each.
A New Hybrid Model for Faculty Hiring Workshops
Fleming, Gabriella Coloyan; Hunt, Grayson; Watson, Del; Mastronardi, Marialice; You, Sally; Contreras, Lydia; Borrego, Maura; Smith, Mark J. T. (2023-09-04)
This paper reports on a new model for faculty hiring workshops involving three components. The first part (Part 1) of the work is an asynchronous, self-guided course that includes video reflections and commentaries from some of our own colleagues about inclusive excellence, hiring legalities, and departmental culture. The second part (Part 2) is a virtual 90-minute interactive session with breakout room discussions overseen by a facilitator. The last part (Part 3) is a monthly offering of optional onehour discussion sessions to answer additional questions, support university-wide conversations and allow participants to probe more deeply into diversity hiring opportunities and challenges. To evaluate the workshops, we administered a survey immediately following Part 2 and later conducted interviews with participants at the conclusion of their faculty search. Survey results show that nearly all elements of the workshops were wellreceived and participants reported feeling confident in their understanding of inclusive excellence, legal issues associated with hiring, and the potential for unintended bias in reviewing candidate files. The paper also provides an analysis of the interview and survey data as well as some conclusions about the impact of these new efforts on inclusive hiring.


