Browsing BioMed Central by Issue Date
Now showing items 1-20 of 345
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Bayesian QTL mapping using skewed Student-tdistributions
(2002-01-15)In most QTL mapping studies, phenotypes are assumed to follow normal distributions. Deviations from this assumption may lead to detection of false positive QTL. To improve the robustness of Bayesian QTL mapping methods, ... -
Optimization of Color Conversion for Face Recognition
(2004-04-21)This paper concerns the conversion of color images to monochromatic form for the purpose of human face recognition. Many face recognition systems operate using monochromatic information alone even when color images are ... -
Editorial
(2004-04-21) -
Calcineurin activation influences muscle phenotype in a muscle-specific fashion
(2004-07-28)Background The calcium activated protein phosphatase 2B, also known as calcineurin, has been implicated as a cell signaling molecule involved with transduction of physiological signals (free cytosolic Ca2+) into molecular ... -
The Catchment Feature Model: A Device for Multimodal Fusion and a Bridge between Signal and Sense
(2004-09-18)The catchment feature model addresses two questions in the field of multimodal interaction: how we bridge video and audio processing with the realities of human multimodal communication, and how information from the different ... -
Review of, "Biostatistics and Epidemiology" by S. Wassertheil-Smoller
(2004-10-19)The entire book review is in the form of an abstract ... some 400 words or less. -
Secondary structure in the target as a confounding factor in synthetic oligomer microarray design
(2005-03-08)Background Secondary structure in the target is a property not usually considered in software applications for design of optimal custom oligonucleotide probes. It is frequently assumed that eliminating self-complementarity, ... -
Comparison of standard exponential and linear techniques to amplify small cDNA samples for microarrays
(2005-05-04)Background The need to perform microarray experiments with small amounts of tissue has led to the development of several protocols for amplifying the target transcripts. The use of different amplification protocols could ... -
Design and Implementation of a DSP-Based MIMO System Prototype for Real-Time Demonstration and Indoor Channel Measurements
(2005-09-21)The design and implementation of the Virginia Tech Space-Time Advanced Radio (VT-STAR), a multiple antenna element space-time (ST) processing prototype testbed, is presented. The testbed is a research tool for comparing ... -
Mitochondrial-encoded membrane protein transcripts are pyrimidine-rich while soluble protein transcripts and ribosomal RNA are purine-rich
(2005-09-26)Background Eukaryotic organisms contain mitochondria, organelles capable of producing large amounts of ATP by oxidative phosphorylation. Each cell contains many mitochondria with many copies of mitochondrial DNA in each ... -
The distribution of SNPs in human gene regulatory regions
(2005-10-06)Background As a result of high-throughput genotyping methods, millions of human genetic variants have been reported in recent years. To efficiently identify those with significant biological functions, a practical strategy ... -
Opportunities for detection and use of QTL influencing seasonal reproduction in sheep: a review
(2005-12-15)Genetic improvement in traits associated with seasonal breeding in sheep is challenging because these traits have low heritabilities, are generally not expressed until late in life, are commonly recorded only in females, ... -
Comparison of assessment techniques: plasma lipid and lipoproteins related to the metabolic syndrome
(2006-01-31)Background The purpose of this investigation was to determine the influence of analytical method on reported concentrations of plasma lipids and lipoproteins, and to determine if there are clinical implications of any ... -
Distinct patterns of SSR distribution in the Arabidopsis thaliana and rice genomes
(2006-02-21)Background Simple sequence repeats (SSRs) in DNA have been traditionally thought of as functionally unimportant and have been studied mainly as genetic markers. A recent handful of studies have shown, however, that SSRs ... -
Molecular targets for rapid identification of Brucellaspp
(2006-02-22)Background Brucella is an intracellular pathogen capable of infecting animals and humans. There are six recognized species of Brucella that differ in their host preference. The genomes of the three Brucella species have ... -
The statistics of identifying differentially expressed genes in Expresso and TM4: a comparison
(2006-04-20)Background Analysis of DNA microarray data takes as input spot intensity measurements from scanner software and returns differential expression of genes between two conditions, together with a statistical significance ... -
XcisClique: analysis of regulatory bicliques
(2006-04-21)Background Modeling of cis-elements or regulatory motifs in promoter (upstream) regions of genes is a challenging computational problem. In this work, set of regulatory motifs simultaneously present in the promoters of a ... -
The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers
(2006-06-19)Background The evolutionary conserved cyclin-dependent kinase phosphatase hCdc14A has been shown to play potential roles in the regulation of mitotic exit and in the centrosome duplication cycle. We have recently shown ... -
FPGA Dynamic Power Minimization through Placement and Routing Constraints
(2006-08-29)Field-programmable gate arrays (FPGAs) are pervasive in embedded systems requiring low-power utilization. A novel power optimization methodology for reducing the dynamic power consumed by the routing of FPGA circuits by ... -
Automatic layout and visualization of biclusters
(2006-09-04)Background Biclustering has emerged as a powerful algorithmic tool for analyzing measurements of gene expression. A number of different methods have emerged for computing biclusters in gene expression data. Many of these ...
