Research conducted at the Virginia Tech Carilion Research Institute (VTCRI) creates a bridge between basic science research at Virginia Tech and clinical expertise at Carilion Clinic and increases translational research opportunities for both partners. Research conducted by scientists at the institute is aimed at understanding the molecular basis for health and disease, and development of diagnostic tools, treatments, and therapies that will contribute to the prevention and solution of existing and emerging problems in contemporary medicine. Research areas of emphasis which presently align with areas of strength and active research at Virginia Tech include inflammation, infectious disease, neuroscience, and cardiovascular science and cardiology.

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Recent Submissions

  • Neuroimaging Strategies Addressing Challenges in Using fMRI for the Children with Cerebral Palsy 

    Lee-Park, Juniper J.; Deshpande, Harshawardhan; Lisinski, Jonathan; LaConte, Stephen; Ramey, Sharon; DeLuca, Stephanie (Scientific Research Publishing Inc., 2018-05-17)
    Aim: This study sought to develop a process and methodology that could be a useful clinical and research tool for successfully completing functional magnetic resonance imaging (fMRI) scanning in children with Cerebral ...
  • A Molecular Toolkit to Visualize Native Protein Assemblies in the Context of Human Disease 

    Gilmore, Brian L.; Winton, Carly E.; Demmert, Andrew C.; Tanner, Justin R.; Bowman, Sam; Karageorge, Vasilea; Patel, Kaya; Sheng, Zhi; Kelly, Deborah F. (Springer Nature, 2015-09-23)
    We present a new molecular toolkit to investigate protein assemblies natively formed in the context of human disease. The system employs tunable microchips that can be decorated with switchable adaptor molecules to select ...
  • Transudative chylothorax in a patient with lymphangioleiomyomatosis 

    Noriega Aldave, Adrian Pedro; Leslie, John W. (Elsevier, 2017-09-30)
    Transudative chylothorax is a rare type of pleural effusion. It has been described to be present in the setting of liver cirrhosis, heart failure, amyloidosis, nephrotic syndrome, superior vena cava thrombosis, sclerosing ...
  • BDNF Val(66)Met Polymorphism Influences Visuomotor Associative Learning and the Sensitivity to Action Observation 

    Taschereau-Dumouchel, Vincent; Hetu, Sebastien; Michon, Pierre-Emmanuel; Vachon-Presseau, Etienne; Massicotte, Elsa; De Beaumont, Louis; Fecteau, Shirley; Poirier, Judes; Mercier, Catherine; Chagnon, Yvon C.; Jackson, Philip L. (Springer Nature, 2016-10-05)
    Motor representations in the human mirror neuron system are tuned to respond to specific observed actions. This ability is widely believed to be influenced by genetic factors, but no study has reported a genetic variant ...
  • Circadian dynamics in measures of cortical excitation and inhibition balance 

    Chellappa, Sarah L.; Gaggioni, Giulia; Ly, Julien Q. M.; Papachilleos, Soterios; Borsu, Chloe; Brzozowski, Alexandre; Rosanova, Mario; Sarasso, Simone; Luxen, Andre; Middleton, Benita; Archer, Simon N.; Dijk, Derk-Jan; Massimini, Marcello; Maquet, Pierre; Phillips, Christophe; Moran, Rosalyn J.; Vandewalle, Gilles (Springer Nature, 2016-09-21)
    Several neuropsychiatric and neurological disorders have recently been characterized as dysfunctions arising from a 'final common pathway' of imbalanced excitation to inhibition within cortical networks. How the regulation ...
  • Implications of Probiotics on the Maternal-Neonatal Interface: Gut Microbiota, Immunomodulation, and Autoimmunity 

    Swartout, Brianna; Luo, Xin M. (Frontiers, 2018-12-03)
    Probiotics are being investigated for the treatment of autoimmune disease by re-balancing dysbiosis induced changes in the immune system. Pregnancy is a health concern surrounding autoimmune disease, both for the mother ...
  • Implantable strain sensor to monitor fracture healing with standard radiography 

    Pelham, Hunter; Benza, Donald; Millhouse, Paul W.; Carrington, Nathan; Arifuzzaman, Md.; Behrend, Caleb J.; Anker, Jeffrey N.; DesJardins, John D. (Springer Nature, 2017-05-04)
    Current orthopaedic clinical methods do not provide an objective measure of fracture healing or weight bearing for lower extremity fractures. The following report describes a novel approach involving in-situ strain sensors ...
  • Genetic determinants restricting the reassortment of heterologous NSP2 genes into the simian rotavirus SA11 genome 

    Mingo, Rebecca; Zhang, Shu; Long, Courtney P.; LaConte, Leslie E. W.; McDonald, Sarah M. (Springer Nature, 2017-08-24)
    Rotaviruses (RVs) can evolve through the process of reassortment, whereby the 11 double-stranded RNA genome segments are exchanged among strains during co-infection. However, reassortment is limited in cases where the genes ...
  • Wellness Weekly, September 7, 2018 

    Unknown author (Virginia Tech, 2018-09-07)
    Weekly recipes, tips, and tricks on improving student wellness from the Virginia Tech Carilion School of Medicine.
  • Wellness Weekly, August 31, 2018 

    Unknown author (Virginia Tech, 2018-08-31)
    Weekly recipes, tips, and tricks on improving student wellness from the Virginia Tech Carilion School of Medicine.
  • Faculty Resources for Educational Excellence (FREE) Newsletter, September 2018 

    Unknown author (Virginia Tech, 2018-09)
    This newsletter focuses each month on some aspect of faculty development, including tips, resources and various opportunities designed to support faculty success at the Virginia Tech Carilion School of Medicine. In this ...
  • Faculty Resources for Educational Excellence (FREE) Newsletter, October 2018 

    Unknown author (Virginia Tech, 2018-10)
    This newsletter focuses each month on some aspect of faculty development, including tips, resources and various opportunities designed to support faculty success at the Virginia Tech Carilion School of Medicine. In this ...
  • Faculty Resources for Educational Excellence (FREE) Newsletter, November 2018 

    Unknown author (Virginia Tech, 2018-11)
    This newsletter focuses each month on some aspect of faculty development, including tips, resources and various opportunities designed to support faculty success at the Virginia Tech Carilion School of Medicine. In this ...
  • Wellness Weekly, August 17, 2018 

    Unknown author (Virginia Tech, 2018-08-17)
    Weekly recipes, tips, and tricks on improving student wellness from the Virginia Tech Carilion School of Medicine.
  • Wellness Weekly, August 24, 2018 

    Unknown author (Virginia Tech, 2018-08-24)
    Weekly recipes, tips, and tricks on improving student wellness from the Virginia Tech Carilion School of Medicine.
  • Wellness Weekly, December 14, 2018 

    Unknown author (Virginia Tech, 2018-12-14)
    Weekly recipes, tips, and tricks on improving student wellness from the Virginia Tech Carilion School of Medicine.
  • Wellness Weekly, November 23, 2018 

    Unknown author (Virginia Tech, 2018-11-23)
    Weekly recipes, tips, and tricks on improving student wellness from the Virginia Tech Carilion School of Medicine.
  • Wellness Weekly, December 7, 2018 

    Unknown author (Virginia Tech, 2018-12-07)
    Weekly recipes, tips, and tricks on improving student wellness from the Virginia Tech Carilion School of Medicine.
  • Faculty Resources for Educational Excellence (FREE) Newsletter, August 2018 

    Unknown author (Virginia Tech, 2018-08)
    This newsletter focuses each month on some aspect of faculty development, including tips, resources and various opportunities designed to support faculty success at the Virginia Tech Carilion School of Medicine. In this ...
  • Wellness Weekly, November 30, 2018 

    Unknown author (Virginia Tech, 2018-11-30)
    Weekly recipes, tips, and tricks on improving student wellness from the Virginia Tech Carilion School of Medicine.

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