Browsing Virginia Tech Carilion (VTC) by Author "Lamouille, Samy"

Now showing items 1-2 of 2

Altered translation initiation of Gja1 limits gap junction formation during epithelial–mesenchymal transition

James, Carissa C.; Zeitz, Michael J.; Calhoun, Patrick J.; Lamouille, Samy; Smyth, James W. (The American Society for Cell Biology, 2018-02-13)

Epithelial–mesenchymal transition (EMT) is activated during development, wound healing, and pathologies including fibrosis and cancer metastasis. Hallmarks of EMT are remodeling of intercellular junctions and adhesion ...
Functional Blockade of Small GTPase RAN Inhibits Glioblastoma Cell Viability

Sheng, Kevin L.; Pridham, Kevin J.; Sheng, Zhi; Lamouille, Samy; Varghese, Robin T. (Frontiers, 2019-01-08)

Glioblastoma, the most common malignant tumor in the brain, lacks effective treatments and is currently incurable. To identify novel drug targets for this deadly cancer, the publicly available results of RNA interference ...